Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: From mechanism to therapy

J Liu, X Han, T Zhang, K Tian, Z Li, F Luo - Journal of Hematology & …, 2023 - Springer
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation
of inflammatory responses is associated with most human diseases. Reactive oxygen …

Biomaterials as therapeutic drug carriers for inflammatory bowel disease treatment

CPJ Wang, MJ Byun, SN Kim, W Park, HH Park… - Journal of Controlled …, 2022 - Elsevier
Inflammatory bowel diseases (IBDs) are idiopathic gastrointestinal inflammatory disorders
featuring chronic intestinal inflammation. Although IBDs are increasingly becoming globally …

Nanoparticle targeting of de novo profibrotic macrophages mitigates lung fibrosis

A Singh, S Chakraborty, SW Wong… - Proceedings of the …, 2022 - National Acad Sciences
The pathogenesis of lung fibrosis involves hyperactivation of innate and adaptive immune
pathways that release inflammatory cytokines and growth factors such as tumor growth …

Non-coding RNA in SARS-CoV-2: progress toward therapeutic significance

H Shirvani, H Jafari, SS Moravveji… - International Journal of …, 2022 - Elsevier
The recently developed pathogenic virus, SARS-CoV-2, was found in the Hubei Province,
China. Giving rise to a broad spectrum of symptoms, SARS-CoV-2 rapidly spread across the …

[HTML][HTML] Nanostructured ceria: Biomolecular templates and (bio) applications

P Rozhin, M Melchionna, P Fornasiero, S Marchesan - Nanomaterials, 2021 - mdpi.com
Ceria (CeO2) nanostructures are well-known in catalysis for energy and environmental
preservation and remediation. Recently, they have also been gaining momentum for …

CNP-miR146a improves outcomes in a two-hit acute-and ventilator-induced lung injury model

AM Wallbank, AE Vaughn, S Niemiec… - … , Biology and Medicine, 2023 - Elsevier
Acute respiratory distress syndrome (ARDS) has high mortality (~ 40%) and requires the
lifesaving intervention of mechanical ventilation. A variety of systemic inflammatory insults …

Emerging application of nanomedicine-based therapy in acute respiratory distress syndrome

Y Xu, L Lv, Q Wang, Q Yao, L Kou, H Zhang - Colloids and Surfaces B …, 2024 - Elsevier
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are serious lung
injuries caused by various factors, leading to increased permeability of the alveolar-capillary …

[HTML][HTML] Lessons from the history of inorganic nanoparticles for inhalable diagnostics and therapeutics

V Uskoković - Advances in Colloid and Interface Science, 2023 - Elsevier
The respiratory tract is one of the most accessible ones to exogenous nanoparticles, yet
drug delivery by their means to it is made extraordinarily challenging because of the plexus …

Macrophage-targeted nanomedicines for ARDS/ALI: Promise and potential

R Vichare, JM Janjic - Inflammation, 2022 - Springer
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by
progressive lung impairment typically triggered by inflammatory processes. The mortality toll …

Assessing the bio-stability of microRNA-146a conjugated nanoparticles via electroanalysis

C El Ghzaoui, CJ Neal, E Kolanthai, Y Fu… - Nanoscale …, 2023 - pubs.rsc.org
The number of diabetics is increasing worldwide and is associated with significant instances
of clinical morbidity. Increased amounts of reactive oxygen species (ROS) and …