The prognostic value of KRAS and BRAF in stage I-III colorectal cancer. A systematic review.

G Gallo, G Sena, G Vescio… - Annali italiani di …, 2019 - annaliitalianidichirurgia.it
BACKGROUND: Colorectal cancer (CRC) is one of the leading cause of cancer deaths
worldwide. The aetiology of CRC is complex and involves interaction on environmental and …

CRISPR/Cas9: a powerful tool in colorectal cancer research

Y Hu, L Liu, Q Jiang, W Fang, Y Chen, Y Hong… - Journal of Experimental …, 2023 - Springer
Colorectal cancer (CRC) is one of the most common malignant cancers worldwide and
seriously threatens human health. The clustered regulatory interspaced short palindromic …

A methylation‐driven gene panel predicts survival in patients with colon cancer

Y Peng, J Zhao, F Yin, G Sharen, Q Wu, Q Chen… - FEBS Open …, 2021 - Wiley Online Library
The accumulation of various genetic and epigenetic changes in colonic epithelial cells has
been identified as one of the fundamental processes that drive the initiation and progression …

LINC00957 acted as prognostic marker was associated with fluorouracil resistance in human colorectal cancer

LH Zhang, LH Li, PF Zhang, YF Cai, D Hua - Frontiers in oncology, 2019 - frontiersin.org
Colorectal cancer (CRC) is one of the most prevalent digestive tumors in China. Recent
studies indicate that long intergenic non-coding RNAs (lincRNAs) play a crucial role in …

Redefining colorectal cancer by tumor biology

ME Salem, A Puccini, J Tie - American Society of Clinical Oncology …, 2020 - ascopubs.org
Colorectal cancer treatment has undergone a paradigm shift. We no longer see this disease
as a singular, anatomic tumor type but rather a set of disease subgroups. Largely because of …

Genomic and epigenomic biomarkers in colorectal cancer: From diagnosis to therapy

J Ruiz-Bañobre, A Goel - Advances in cancer research, 2021 - Elsevier
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United
States. Despite ongoing efforts aimed at increasing screening for CRC and early detection …

[HTML][HTML] PNN and KCNQ1OT1 can predict the efficacy of adjuvant fluoropyrimidine-based chemotherapy in colorectal cancer patients

A Lapucci, G Perrone, A Di Paolo, C Napoli… - Oncology …, 2021 - ncbi.nlm.nih.gov
The benefit of adjuvant chemotherapy in the early stages of colorectal cancer (CRC) is still
disappointing and the prediction of treatment outcome quite difficult. Recently, through a …

Tumor suppressor miR‐193a‐3p enhances efficacy of BRAF/MEK inhibitors in BRAF‐mutated colorectal cancer

S Hiraide, M Takahashi, Y Yoshida, H Yamada… - Cancer …, 2021 - Wiley Online Library
Patients with BRAF‐mutated colorectal cancer (CRC) have a poor prognosis despite recent
therapeutic advances such as combination therapy with BRAF, MEK, and epidermal growth …

High microsatellite instability (MSI-H) is associated with distinct clinical and molecular characteristics and an improved survival in early Colon cancer (CC); real world …

S Noepel-Duennebacke, H Juette… - Zeitschrift für …, 2020 - thieme-connect.com
Colorectal cancer is one of the leading malignancies and still accounts for almost 25 000
deaths in Germany each year. Although there is accumulating data on the molecular basis …

Identification of fatty acid metabolism-related lncRNAs in the prognosis and immune microenvironment of colon adenocarcinoma

S Wu, Y Gong, J Chen, X Zhao, H Qing, Y Dong, S Li… - Biology Direct, 2022 - Springer
Background Cancer metabolism is largely altered compared to normal cells. This study aims
to explore critical metabolism pathways in colon adenocarcinoma (COAD), and reveal the …