Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …

Calcitonin-gene-related peptide (CGRP) and adrenomedullin are related peptides with
distinct pharmacological profiles. Here we show that a receptor with seven transmembrane …

This review summarizes the receptor-mediated vascular activities of calcitonin gene-related
peptide (CGRP) and the structurally related peptide adrenomedullin (AM). CGRP is a 37 …

Since the discovery of adrenomedullin in 1993 several hundred papers have been
published regarding the regulation of its secretion and the multiplicity of its actions. It has …

The calcitonin family of peptides comprises calcitonin, amylin, two calcitonin gene-related
peptides (CGRPs), and adrenomedullin. The first calcitonin receptor was cloned in 1991. Its …

The biological clock, the suprachiasmatic nucleus (SCN), is essential for our daily well-
being. It prepares us for the upcoming period of activity by an anticipatory rise in heart rate …

Calcitonin gene‐related peptide (CGRP) is one of the most potent endogenous vasodilators
known. This peptide is increased during migraine attacks and has been implicated in the …

I. Introduction T HE calcitonin (CT) and calcitonin gene-related peptide (CGRP) are derived
from the CT/CGRP gene, which is localized in chromosome 11. Alternative splicing of the …