The humoral response and antibodies against SARS-CoV-2 infection
Two and a half years into the COVID-19 pandemic, we have gained many insights into the
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …
Distinguishing features of current COVID-19 vaccines: knowns and unknowns of antigen presentation and modes of action
FX Heinz, K Stiasny - npj Vaccines, 2021 - nature.com
COVID-19 vaccines were developed with an unprecedented pace since the beginning of the
pandemic. Several of them have reached market authorization and mass production …
pandemic. Several of them have reached market authorization and mass production …
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2
Although two-dose mRNA vaccination provides excellent protection against SARS-CoV-2,
there is little information about vaccine efficacy against variants of concern (VOC) in …
there is little information about vaccine efficacy against variants of concern (VOC) in …
Mutations and evolution of the SARS-CoV-2 spike protein
The SARS-CoV-2 spike protein mediates target recognition, cellular entry, and ultimately the
viral infection that leads to various levels of COVID-19 severities. Positive evolutionary …
viral infection that leads to various levels of COVID-19 severities. Positive evolutionary …
SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies
Several variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have
emerged during the current coronavirus disease 2019 (COVID-19) pandemic. Although …
emerged during the current coronavirus disease 2019 (COVID-19) pandemic. Although …
The impact of evolving SARS-CoV-2 mutations and variants on COVID-19 vaccines
The emergence of several new variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in recent months has raised concerns around the potential impact on …
(SARS-CoV-2) in recent months has raised concerns around the potential impact on …
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains
Rapidly emerging SARS-CoV-2 variants jeopardize antibody-based countermeasures.
Although cell culture experiments have demonstrated a loss of potency of several anti-spike …
Although cell culture experiments have demonstrated a loss of potency of several anti-spike …
Immune evasion of SARS-CoV-2 emerging variants: what have we learnt so far?
I Lazarevic, V Pravica, D Miljanovic, M Cupic - Viruses, 2021 - mdpi.com
Despite the slow evolutionary rate of SARS-CoV-2 relative to other RNA viruses, its massive
and rapid transmission during the COVID-19 pandemic has enabled it to acquire significant …
and rapid transmission during the COVID-19 pandemic has enabled it to acquire significant …
New coronavirus variants are creating more challenges to global healthcare system: a brief report on the current knowledge
The coronavirus is naturally mutating over time and producing new variants. Some of them
are more contagious and destructive than previous strains. Also, some variants are capable …
are more contagious and destructive than previous strains. Also, some variants are capable …
The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?
RJ Boyton, DM Altmann - Nature Reviews Immunology, 2021 - nature.com
An important challenge during the COVID-19 pandemic has been to understand
asymptomatic disease and the extent to which this may be a source of transmission. As …
asymptomatic disease and the extent to which this may be a source of transmission. As …