Neuroinflammation is a key factor of the pathology of various neurological diseases (brain
injury, depression, neurodegenerative diseases). It is a complex and orderly process that …

Numerous studies have highlighted the role of post-translational modifications in the
regulation of cell proliferation, differentiation and death. Among these modifications …

As one of the most common post-transcriptional modifications of mRNAs and noncoding
RNAs, N 6-methyladenosine (m 6 A) modification regulates almost every aspect of RNA …

Abstract Histone deacetylase 1 (HDAC1) is known to participate in the molecular etiology of
polycystic ovary syndrome (PCOS). However, its role in granulosa cell (GC) pyroptosis …

Iron deficiency is a common micronutrient deficiency associated with metabolic changes in
the levels of iron regulatory proteins, hepcidin and ferroportin. Studies have associated …

Peptide labeling by isobaric tags is a powerful approach for the relative quantitative analysis
of proteomes in multiple groups. There has been a revolution in the innovation of new …

Histone deacetylases (HDACs) are critical immune regulators. However, their roles in
interleukin-1β (IL-1β) production remain unclear. By screening 11 zinc-dependent HDACs …

Abstract Context Danggui Buxue Decoction (DBD) is an effective complementary medicine
in alleviating myelosuppression after chemotherapy (MAC). However, its mechanism of …

Abnormal expression of Cylindromatosis (CYLD), a tumor suppressor molecule, plays an
important role in tumor development and treatment. In this work, we found that CYLD binds …

Simple Summary Histone deacetylase (HDAC) inhibitors are anti-cancer agents that have
demonstrated efficacy in hematologic malignancies; however, the utility of available agents …