Hypericin as a promising natural bioactive naphthodianthrone: A review of its pharmacology, pharmacokinetics, toxicity, and safety

Z Peng, J Lu, K Liu, L Xie, Y Wang, C Cai… - Phytotherapy …, 2023 - Wiley Online Library
Hypericin can be derived from St. John's wort, which is widely spread around the world. As a
natural product, it has been put into clinical practice such as wound healing and depression …

Prokaryotic and eukaryotic toxicity of halloysite decorated with photoactive nanoparticles

A Stavitskaya, E Khusnetdenova, V Vinokurov… - Chemical …, 2022 - pubs.rsc.org
The development of new approaches to treat the growing antibiotic resistance of pathogenic
bacterial species is an important task to ensure the future safety of society. Utilization of …

Near‐infrared light‐mediated cyclodextrin metal–organic frameworks for synergistic antibacterial and anti‐biofilm therapies

Y He, X Wang, C Zhang, J Sun, J Xu, D Li - Small, 2023 - Wiley Online Library
Bacterial infections pose a significant threat to global public health; therefore, the
development of novel therapeutics is urgently needed. Herein, a controllable antibacterial …

Trial watch: an update of clinical advances in photodynamic therapy and its immunoadjuvant properties for cancer treatment

M Penetra, LG Arnaut, LC Gomes-da-Silva - 2023 - Taylor & Francis
Photodynamic therapy (PDT) is a medical treatment used to target solid tumors, where the
administration of a photosensitizing agent and light generate reactive oxygen species …

The interaction of hypericin with SARS-CoV-2 reveals a multimodal antiviral activity

P Delcanale, E Uriati, M Mariangeli… - … Applied Materials & …, 2022 - ACS Publications
Hypericin is a photosensitizing drug that is active against membrane-enveloped viruses and
therefore constitutes a promising candidate for the treatment of SARS-CoV-2 infections. The …

Antibacterial photodynamic therapy in the near-infrared region with a targeting antimicrobial peptide connected to a π-extended porphyrin

C Gourlot, A Gosset, E Glattard… - ACS Infectious …, 2022 - ACS Publications
The increase of antimicrobial resistance to conventional antibiotics is worldwide a major
health problem that requires the development of new bactericidal strategies. Antimicrobial …

[HTML][HTML] Photodynamic disinfection of SARS-CoV-2 clinical samples using a methylene blue formulation

CS Lobo, P Rodrigues-Santos, D Pereira… - Photochemical & …, 2022 - Springer
The amplitude of the coronavirus disease 2019 (COVID-19) pandemic motivated global
efforts to find therapeutics that avert severe forms of this illness. The urgency of the medical …

[HTML][HTML] Synergic dual phototherapy: Cationic imidazolyl photosensitizers and ciprofloxacin for eradication of in vitro and in vivo E. coli infections

RT Aroso, LD Dias, KC Blanco, JM Soares… - … of Photochemistry and …, 2022 - Elsevier
The emergence of new microorganisms with resistance to current antimicrobials is one of
the key issues of modern healthcare that must be urgently addressed with the development …

Photosensitizers combination approach to enhance photodynamic inactivation of planktonic and biofilm bacteria

MB Spesia, EN Durantini - Photochemical & Photobiological Sciences, 2023 - Springer
To improve bacterial photodynamic inactivation (PDI), this work analyzes the photodynamic
effect caused by the combination of photosensitizers (PSs) on two bacterial models and …

[HTML][HTML] Sulphur-and selenium-for-oxygen replacement as a strategy to obtain dual Type I/Type II photosensitizers for photodynamic therapy

M Prejanò, ME Alberto, BC De Simone, T Marino… - Molecules, 2023 - mdpi.com
The effect on the photophysical properties of sulfur-and selenium-for-oxygen replacement in
the skeleton of the oxo-4-dimethylaminonaphthalimide molecule (DMNP) has been explored …