CRISPR/Cas9 therapeutics: progress and prospects

T Li, Y Yang, H Qi, W Cui, L Zhang, X Fu, X He… - … and Targeted Therapy, 2023 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …

Sex and gender: modifiers of health, disease, and medicine

F Mauvais-Jarvis, NB Merz, PJ Barnes, RD Brinton… - The Lancet, 2020 - thelancet.com
Clinicians can encounter sex and gender disparities in diagnostic and therapeutic
responses. These disparities are noted in epidemiology, pathophysiology, clinical …

Health risks and outcomes that disproportionately affect women during the Covid-19 pandemic: A review

J Connor, S Madhavan, M Mokashi, H Amanuel… - Social science & …, 2020 - Elsevier
Abstract Background The Covid-19 pandemic is straining healthcare systems in the US and
globally, which has wide-reaching implications for health. Women experience unique health …

Spontaneous coronary artery dissection: current state of the science: a scientific statement from the American Heart Association

SN Hayes, ESH Kim, J Saw, D Adlam… - Circulation, 2018 - Am Heart Assoc
Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of
acute coronary syndrome, myocardial infarction, and sudden death, particularly among …

Sex differences in blood pressure trajectories over the life course

H Ji, A Kim, JE Ebinger, TJ Niiranen… - JAMA …, 2020 - jamanetwork.com
Importance If we assume that women and men exhibit variations of the same fundamental
vascular physiology, then conventional analyses of subclinical measures would suggest that …

[HTML][HTML] Implicit bias in healthcare: clinical practice, research and decision making

DP Gopal, U Chetty, P O'Donnell, C Gajria… - Future healthcare …, 2021 - Elsevier
Bias is the evaluation of something or someone that can be positive or negative, and implicit
or unconscious bias is when the person is unaware of their evaluation. This is particularly …

Cardiovascular disease and breast cancer: where these entities intersect: a scientific statement from the American Heart Association

LS Mehta, KE Watson, A Barac, TM Beckie, V Bittner… - Circulation, 2018 - Am Heart Assoc
Cardiovascular disease (CVD) remains the leading cause of mortality in women, yet many
people perceive breast cancer to be the number one threat to women's health. CVD and …

Sex and gender in cardiovascular medicine: presentation and outcomes of acute coronary syndrome

A Haider, S Bengs, J Luu, E Osto… - European heart …, 2020 - academic.oup.com
Although health disparities in women presenting with acute coronary syndrome (ACS) have
received growing attention in recent years, clinical outcomes from ACS are still worse for …

Childhood and adolescent adversity and cardiometabolic outcomes: a scientific statement from the American Heart Association

SF Suglia, KC Koenen, R Boynton-Jarrett, PS Chan… - Circulation, 2018 - Am Heart Assoc
Adverse experiences in childhood and adolescence, defined as subjectively perceived
threats to the safety or security of the child's bodily integrity, family, or social structures, are …

Sex-specific differences in hypertension and associated cardiovascular disease

KMM Colafella, KM Denton - Nature Reviews Nephrology, 2018 - nature.com
Although intrinsic mechanisms that regulate arterial blood pressure (BP) are similar in men
and women, marked variations exist at the molecular, cellular and tissue levels. These …