Corticosteroids in COVID-19: pros and cons

A Bahsoun, Y Fakih, R Zareef, F Bitar, M Arabi - Frontiers in Medicine, 2023 - frontiersin.org
The wide and rapid spread of the COVID-19 pandemic has placed an unanticipated burden
on the global healthcare sector. This necessitated a swift response from the international …

Therapeutic implications of current Janus kinase inhibitors as anti-COVID agents: A review

NK Jain, M Tailang, HK Jain… - Frontiers in …, 2023 - frontiersin.org
Severe cases of COVID-19 are characterized by hyperinflammation induced by cytokine
storm, ARDS leading to multiorgan failure and death. JAK-STAT signaling has been …

Sarilumab administration in COVID-19 patients: Literature review and considerations

A Marino, A Munafò, E Augello, CM Bellanca… - Infectious Disease …, 2022 - mdpi.com
Two years have passed since WHO declared a pandemic state for SARS-CoV-2 infection.
COVID-19 pathogenesis consists of a first viral phase responsible for early symptoms …

Comprehensive studies of the anti-inflammatory effect of tetraprenyltoluquinone, a quinone from Garcinia cowa Roxb

IP Dewi, Y Aldi, NH Ismail, D Hefni, M Susanti… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Garcinia cowa Roxb. is called asam kandis in
West Sumatra. This plant contains several quinone compounds, including …

Investigating the promising SARS-CoV-2 main protease inhibitory activity of secoiridoids isolated from Jasminum humile; in silico and in Vitro assessments with …

AA Al-Karmalawy, R Alnajjar, AA Elmaaty… - Journal of …, 2023 - Taylor & Francis
The proteolytic enzyme 3 C-like protease (3Clpro or Mpro) is considered the most important
target for SARS-CoV-2 which could be attributed to its crucial role in viral maturation and/or …

[HTML][HTML] Immune Dysregulation during and after COVID-19:“Tomorrow Never Dies” Situation

S Patil, S Patil, G Gondhali… - Journal of Translational …, 2023 - journals.lww.com
Coronavirus disease 2019 (COVID-19) pandemic has been studied over last two and half
years for its highly pathogenic nature of corona virus. Main hurdle for acquiring …

The efficacy of herbal medicines on the length of stay and negative conversion time/rate outcomes in patients with COVID-19: a systematic review

IR Latarissa, A Meiliana, IP Sormin… - Frontiers in …, 2024 - frontiersin.org
Introduction In recent years, diverse initiatives have been carried out to control the COVID-
19 pandemic, ranging from measures restricting social activities to analyzing drugs and …

Cardiac auscultation predicts mortality in elderly patients admitted for COVID-19

N Roig-Marín, P Roig-Rico - Hospital Practice, 2022 - Taylor & Francis
Introduction COVID-19 has had a great impact on the elderly population. All admitted
patients underwent cardiac auscultation at the Emergency Department. However, to our …

[HTML][HTML] Combination therapies against COVID-19

Q Luo, Y Zheng, J Zhang - Frontiers in Bioscience-Landmark, 2022 - imrpress.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
Coronavirus disease 2019 (COVID-19), which was announced as a pandemic leading to …

Early administration of tofacitinib in COVID‐19 pneumonitis: an open randomised controlled trial

A Ferrarini, A Vacca, AG Solimando… - European Journal of …, 2023 - Wiley Online Library
Background Controversies on sub‐populations most sensitive to therapy and the best timing
of starting the treatment still surround the use of immunomodulatory drugs in COVID‐19 …