Fracture-related infection in osteoporotic bone causes more severe infection and further delays healing

J Li, RMY Wong, YL Chung, SSY Leung… - Bone & Joint …, 2022 - boneandjoint.org.uk
Aims With the ageing population, fragility fractures have become one of the most common
conditions. The objective of this study was to investigate whether microbiological outcomes …

High-frequency loading positively impacts titanium implant osseointegration in impaired bone

M Chatterjee, K Hatori, J Duyck, K Sasaki, I Naert… - Osteoporosis …, 2015 - Springer
High-frequency loading via whole body vibration promotes bone formation and increases
bone strength. Whether this translates to positive titanium implant osseointegration in …

Investigation of rat bone fracture healing using pulsed 1.5 MHz, 30 mW/cm2 burst ultrasound–axial distance dependency

CH Fung, WH Cheung, NM Pounder, FJ de Ana… - Ultrasonics, 2014 - Elsevier
This study investigated the effect of LIPUS on fracture healing when fractures were exposed
to ultrasound at three axial distances: z= 0 mm, 60 mm, and 130 mm. We applied LIPUS to …

Therapeutic effects of whole-body vibration on fracture healing in ovariectomized rats: a systematic review and meta-analysis

J Chen, H Ruan, Y Liu, J Bao, H Xu, M Yao, X Cui… - Menopause, 2019 - journals.lww.com
Objective: Whole-body vibration (WBV), providing cyclic mechanical stimulation, has been
used to accelerate fracture healing in preclinical studies. This study aimed to summarize and …

Discretizing low‐intensity whole‐body vibration into bouts with short rest intervals promotes bone defect repair in osteoporotic mice

T Matsumoto, K Hashimoto… - Journal of Orthopaedic …, 2024 - Wiley Online Library
Continuous administration of low‐intensity whole‐body vibration (WBV) gradually
diminishes bone mechanosensitivity over time, leading to a weakening of its osteogenic …

Effects of continuous or intermittent low-magnitude high-frequency vibration on fracture healing in sheep

Y Li, G Liu, J Yu, C Li, L Tan, B Hao, C Liu, J Lin… - International …, 2018 - Springer
Purpose Vibration therapy has been shown to improve fracture healing. In this study, we
investigated the effects of continuous or different intermittent vibration regimens on fracture …

Application of low intensity mechanical vibrations for bone tissue maintenance and regeneration

MO Uzan, Ö Baskan, Ö Karadaş… - Turkish Journal of …, 2016 - journals.tubitak.gov.tr
Physical exercise is beneficial for bone tissue health, yet its usage is limited for preventing
osteoporosis. Even though natural for the bone tissue from development to homeostasis …

Bioinformatics analysis combined with molecular dynamics simulation validation to elucidate the potential molecular mechanisms of Jianshen Decoction for treatment …

W Liu, W Chen, M Hu, G Wang, Y Hu, Q He, Y Xu… - Medicine, 2023 - journals.lww.com
Osteoporotic fracture (OPF) is a prevalent skeletal disease in the middle-aged and elderly. In
clinical practice, Jianshen Decoction (JSD) has been used to treat OPFs. However, the …

Osteocyte-specific dentin matrix protein 1: the role of mineralization regulation in low-magnitude high-frequency vibration enhanced osteoporotic fracture healing

MCM Li, SKH Chow, RMY Wong, B Chen… - Bone & Joint …, 2022 - boneandjoint.org.uk
Aims There is an increasing concern of osteoporotic fractures in the ageing population. Low-
magnitude high-frequency vibration (LMHFV) was shown to significantly enhance …

[HTML][HTML] Preclinical mouse models for assessing axial compression of long bones during exercise

VA Stadelmann, J Brun, N Bonnet - BoneKEy reports, 2015 - ncbi.nlm.nih.gov
The aim of this laboratory method is to describe two approaches for the investigation of bone
responses to mechanical loading in mice in vivo. The first is running exercise, because it is …