The disturbance of gaze in progressive supranuclear palsy: implications for pathogenesis

AL Chen, DE Riley, SA King, AC Joshi, A Serra… - Frontiers in …, 2010 - frontiersin.org
Progressive supranuclear palsy (PSP) is a disease of later life that is currently regarded as a
form of neurodegenerative tauopathy. Disturbance of gaze is a cardinal clinical feature of …

Vestibular deficits in neurodegenerative disorders: balance, dizziness, and spatial disorientation

T Cronin, Q Arshad, BM Seemungal - Frontiers in neurology, 2017 - frontiersin.org
The vestibular system consists of the peripheral vestibular organs in the inner ear and the
associated extensive central nervous system projections—from the cerebellum and …

[HTML][HTML] Abnormal eye movements in parkinsonism and movement disorders

I Jung, JS Kim - Journal of movement disorders, 2019 - ncbi.nlm.nih.gov
Abnormal eye movements are commonly observed in movement disorders. Ocular motility
examination should include bedside evaluation and laboratory recording of ocular …

Visual signs and symptoms of progressive supranuclear palsy

RA Armstrong - Clinical and Experimental Optometry, 2011 - Taylor & Francis
Progressive supranuclear palsy is a rare, degenerative brain disorder and the second most
common syndrome in which the patient exhibits 'parkinsonism', that is, a variety of symptoms …

Why do patients with PSP fall? Evidence for abnormal otolith responses

K Liao, J Wagner, A Joshi, I Estrovich, MF Walker… - Neurology, 2008 - AAN Enterprises
Background: Patients with progressive supranuclear palsy (PSP) fall frequently, beginning
early in the course of their disease. Abnormal vestibulospinal reflexes are suspected, but the …

Head orientation and gait stability in young adults, dancers and older adults

RM Magnani, SM Bruijn, JH van Dieen, MF Vieira - Gait & Posture, 2020 - Elsevier
Background Control of body orientation requires head motion detection by the vestibular
system and small changes with respect to the gravitational acceleration vector could cause …

The neuroanatomical basis of oculomotor disorders: the dual motor control of extraocular muscles and its possible role in proprioception

JA BuÈttner-Ennever, AKE Horn - Current opinion in neurology, 2002 - journals.lww.com
Current investigations show that two separate sets of motoneurons control the extraocular
eye muscles, and that is there is a dual final common pathway. We propose that one set of …

Characteristics of vestibular corrective saccades in patients with slow visual saccades, vestibular disorders and controls: A descriptive analysis

DA Yacovino, LA Martin, M Perez Akly, TC Hain - Plos one, 2018 - journals.plos.org
Objective Our aim was to determine whether overt catch up saccades (OS) provoked by
vestibular stimuli, as observed in the video head impulse test (vHIT), have comparable …

Progressive supranuclear palsy: Neuropathology, clinical presentation, diagnostic challenges, management, and emerging therapies

F DeRosier, C Hibbs, K Alessi, I Padda, J Rodriguez… - Disease-a-Month, 2024 - Elsevier
Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by the
accumulation of 4R-tau protein aggregates in various brain regions. PSP leads to neuronal …

The linear vestibulo-ocular reflex, locomotion and falls in neurological disorders

K Liao, MF Walker, AC Joshi… - Restorative …, 2010 - content.iospress.com
Purpose: During locomotion, head perturbations, consisting of rotations and translations
(linear movements), occur with predominant frequencies of 0.5–5.0 Hz. The vestibular …