The potential for ischemic preconditioning to reduce infarct size was first recognized more
than 30 years ago [180]. Despite extension of the concept to ischemic postcondition‑ing …

Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability
in most patients with estrogen receptor positive breast cancers (ER+ BC). By genomic and …

Antibacterial activity of zinc oxide nanoparticles (ZnO-NPs) has received significant interest
worldwide particularly by the implementation of nanotechnology to synthesize particles in …

Generation, transformation, and utilization of organic molecules in support of cellular
differentiation, growth, and maintenance are basic tenets that define life. In eukaryotes …

The heme peroxidase family generates a battery of oxidants both for synthetic purposes, and
in the innate immune defence against pathogens. Myeloperoxidase (MPO) is the most …

Reactive oxygen species (ROS) at the right concentration promote cell proliferation in cell
culture, stem cells, and model organisms. However, the mystery of how ROS signaling is …

Recently, it was proposed that there is a common mechanism behind the activity of
bactericidal antibiotics, involving the production of reactive oxygen species (ROS). However …

Oxidative stress is implicated in the pathogenesis and progression of Alzheimer's disease
(AD) and its earlier stage, amnestic mild cognitive impairment (aMCI). One source of …

Neutrophils are essential for killing bacteria and other microorganisms, and they also have a
significant role in regulating the inflammatory response. Stimulated neutrophils activate their …

The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …