Patient-reported outcomes (PROs) are used in clinical trials to provide valuable evidence on
the impact of disease and treatment on patients' symptoms, function and quality of life. High …

Aims: Quality of life (QoL) assessment is frequently not included among the end points of
clinical trials (CTs) on renal cell carcinoma. Herein we aimed to describe the assessment …

Importance Although bevacizumab is a standard of care in combination treatments for
metastatic colorectal cancer (mCRC), its clinical benefit has been limited. Objective To …

Simple Summary Bowel cancer is one of the leading cancer-types in both sexes worldwide.
Despite that most new cases and deaths occur in people aged 70 years or older, few clinical …

Simple Summary Metastatic colorectal cancer is the second most common cause of cancer
death. Long-term survival and cure can be achieved after intensive treatments, including …

Introduction The RECOURSE trial demonstrated a modest benefit in overall survival (OS) for
trifluridine/tipiracil (FTD/TPI) versus placebo in pretreated metastatic colorectal cancer …

Multimodal interventions including nutrition have the potential to improve patient-centred
outcomes in older adults with cancer during the continuum of care, from prehabilitation to …

Opinion statement Treatment guidelines for colorectal cancer (CRC) are primarily based on
the results of randomized clinical trials (RCTs), the gold standard methodology to evaluate …

Patient experience data (PED), provided by patients/their carers without interpretation by
clinicians, directly capture what matters more to patients on their medical condition …

Over the past decades, anti-cancer treatments have evolved rapidly from cytotoxic
chemotherapies to targeted therapies including oral targeted medications and injectable …