COVID‐19 in early 2023: Structure, replication mechanism, variants of SARS‐CoV‐2, diagnostic tests, and vaccine & drug development studies

I Polatoğlu, T Oncu‐Oner, I Dalman, S Ozdogan - MedComm, 2023 - Wiley Online Library
Abstract Coronavirus Disease‐19 (COVID‐19) is an infectious disease caused by severe
acute respiratory syndrome‐coronaviruses‐2 (SARS‐CoV‐2), a highly pathogenic and …

SARS‐CoV‐2 papain‐like protease: structure, function and inhibition

S Ullrich, C Nitsche - Chembiochem, 2022 - Wiley Online Library
Emerging variants of SARS‐CoV‐2 and potential novel epidemic coronaviruses underline
the importance of investigating various viral proteins as potential drug targets. The papain …

Safety and efficacy of COVID‐19 vaccines: A systematic review and meta‐analysis of controlled and randomized clinical trials

J Beladiya, A Kumar, Y Vasava… - Reviews in Medical …, 2024 - Wiley Online Library
Vaccines against coronavirus disease 2019 (COVID‐19) have been discovered within a
very small duration of time as compared to the traditional way for the development of …

Vaccines and monoclonal antibodies: new tools for malaria control

K Miura, Y Flores-Garcia, CA Long… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

COVID-19 vaccines: an updated overview of different platforms

D Kudlay, A Svistunov, O Satyshev - Bioengineering, 2022 - mdpi.com
Vaccination has been identified as a critical method of disease control in the context of the
current COVID-19 pandemic. The goal of this review is to update information on vaccine …

Pooled rates and demographics of POTS following SARS-CoV-2 infection versus COVID-19 vaccination: Systematic review and meta-analysis

SJ Yong, A Halim, S Liu, M Halim, AA Alshehri… - Autonomic …, 2023 - Elsevier
Purpose To address recent concerns of postural orthostatic tachycardia syndrome (POTS)
occurring after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Antioxidants and clinical outcomes of patients with coronavirus disease 2019: A systematic review of observational and interventional studies

S Foshati, F Mirjalili, M Rezazadegan… - Food Science & …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is a newly emerging viral infection caused
by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Oxidative stress …

A Polysaccharide-RBD-Fc-Conjugated COVID-19 vaccine, SCTV01A, showed high immunogenicity and low toxicity in animal models

C Sun, D Kong, E Guo, J Zhao, J Jia, R Wang, J Ma… - Vaccines, 2023 - mdpi.com
We previously developed a polysaccharide-–RBD-conjugated nanoparticle vaccine which
induced protective efficacy against SARS-CoV-2 in a mouse model. Here, we newly …

[HTML][HTML] Real-world effectiveness of the inactivated COVID-19 vaccines against variant of concerns: meta-analysis

MU Sarwar, FZ Waasia, AA Aloqbi… - Journal of Infection and …, 2024 - Elsevier
Background COVID-19 has killed over 6 million people worldwide, making it the worst global
health disaster since the 1918 influenza pandemic. Experts have worked to establish the …

Antivirals for broader coverage against human coronaviruses

M Outteridge, CM Nunn, K Devine, B Patel, GR McLean - Viruses, 2024 - mdpi.com
Coronaviruses (CoVs) are enveloped positive-sense single-stranded RNA viruses with a
genome that is 27–31 kbases in length. Critical genes include the spike (S), envelope (E) …