Diagnostic and prognostic value of galactose-deficient IgA1 in patients with IgA nephropathy: an updated systematic review with meta-analysis

Q Zeng, WR Wang, YH Li, Y Liang, XH Wang… - Frontiers in …, 2023 - frontiersin.org
Objectives Galactose-deficient IgA1 (Gd-IgA1) is a critical effector molecule in the
pathogenesis of IgA nephropathy (IgAN), a leading renal disease without noninvasive …

Exploration of artemisinin against IgA nephropathy via AKT/Nrf2 pathway by bioinformatics and experimental validation

W Yang, A Sun, R Zhu, N Liu, W He… - … Design, Development and …, 2023 - Taylor & Francis
Background Artemisinin (ART) is a safe and effective antimalarial drug. In recent years,
antimalarial drugs have demonstrated a good therapeutic efficacy in IgA nephropathy …

Humoral immune responses primed by the alteration of gut microbiota were associated with galactose-deficient IgA1 production in IgA nephropathy

L Gao, H Li, X Liu, H Li, P Li, W Lu, X Xie, J Lv… - Frontiers in …, 2024 - frontiersin.org
Introduction Galactose-deficient IgA1 (GdIgA1) is critical in the formation of immunodeposits
in IgA nephropathy (IgAN), whereas the origin of GdIgA1 is unknown. We focused on the …

Differences of clinicopathological characteristics and outcomes of IgA nephropathy patients with and without nephrotic syndrome

N Huang, J Li, Z Ai, L Guo, W Chen, Q Liu - International Urology and …, 2024 - Springer
Purpose To evaluate the differences in clinicopathological features and outcomes of IgA
nephropathy (IgAN) patients with and without nephrotic syndrome. Methods In this …

Characterization of patients with IgA nephropathy with and without associated minimal change disease

W Guo, L Sun, H Dong, G Wang, X Xu… - Frontiers in …, 2023 - frontiersin.org
Introduction Immunoglobulin A nephropathy (IgAN) presents various clinical manifestations
and pathological phenotypes. Approximately 5% of patients with IgAN present with early …