Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Few studies have explored the impact of rare variants (minor allele frequency< 1%) on
highly heritable plasma metabolites identified in metabolomic screens. The Finnish …

Background Exome sequencing in hundreds of thousands of persons may enable the
identification of rare protein-coding genetic variants associated with protection from human …

Gestational diabetes mellitus (GDM) is associated with increased risk of pregnancy
complications and adverse perinatal outcomes. GDM often reoccurs and is associated with …

Our genetic background has not changed over the past century, but chronic diseases are on
the rise globally. In addition to the genetic component, among the critical factors for many …

As an environmental toxicant, the damage of fluoride to the body has attracted global
attention. Because liver is an essential organ for fluoride accumulation and damage. Our …

Aerobic glycolysis is the primary energy supply mode for glioblastoma (GBM) cells to
maintain growth and proliferation. However, due to the metabolic reprogramming of tumor …

Telomere length and risk of cirrhosis, hepatocellular carcin... : Hepatology Telomere length and
risk of cirrhosis, hepatocellular carcinoma, and cholangiocarcinoma in 63,272 individuals from …

As a vital bacteria-secreted toxin, hydrogen peroxide (H 2 O 2) can destroy infected tissues
and increase vascular permeability, leading to life-threatening systemic bacteremia or …

Temozolomide (TMZ) is a conventional chemotherapeutic drug for glioma, however, its
clinical application and efficacy is severely restricted by its drug resistance properties. O6 …