Dietary protection against cognitive impairment, Neuroinflammation and oxidative stress in Alzheimer's disease animal models of lipopolysaccharide-induced …

D Decandia, F Gelfo, E Landolfo, F Balsamo… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a rapidly growing epidemic with a heavy social and economic
burden. Evidence suggests that systemic inflammation, dysregulation of the immune …

Sustained CREB phosphorylation by lipid-peptide liquid crystalline nanoassemblies

Y Wu, B Angelov, Y Deng, T Fujino… - Communications …, 2023 - nature.com
Cyclic-AMP-response element-binding protein (CREB) is a leucine zipper class transcription
factor that is activated through phosphorylation. Ample CREB phosphorylation is required for …

Lipid and Transcriptional Regulation in a Parkinson's Disease Mouse Model by Intranasal Vesicular and Hexosomal Plasmalogen‐Based Nanomedicines

Y Wu, J Wang, Y Deng, B Angelov… - Advanced …, 2024 - Wiley Online Library
Plasmalogens (vinyl‐ether phospholipids) are an emergent class of lipid drugs against
various diseases involving neuro‐inflammation, oxidative stress, mitochondrial dysfunction …

Promising Strategies to Reduce the SARS-CoV-2 Amyloid Deposition in the Brain and Prevent COVID-19-Exacerbated Dementia and Alzheimer's Disease

N Navolokin, V Adushkina, D Zlatogorskaya… - Pharmaceuticals, 2024 - mdpi.com
The COVID-19 pandemic, caused by infection with the SARS-CoV-2 virus, is associated with
cognitive impairment and Alzheimer's disease (AD) progression. Once it enters the brain, the …

In Vitro Evaluation of the Effects of 7-Ketocholesterol and 7β-Hydroxycholesterol on the Peroxisomal Status: Prevention of Peroxisomal Damages and Concept of …

I Ghzaiel, S Maaloul, M Ksila, A Namsi… - Implication of Oxysterols …, 2023 - Springer
Ketocholesterol and 7β-hydroxycholesterol are most often derived from the autoxidation of
cholesterol. Their quantities are often increased in the body fluids and/or diseased organs of …

海参功能活性研究进展.

崔保金, 曹荣, 宋文, 赵玲, 刘淇… - Journal of Food Safety …, 2023 - search.ebscohost.com
海参是我国传统的滋补佳品, 有着悠久的消费历史, 深受消费者欢迎. 近年来随着对海参生物活性
物质, 包括海参多糖, 蛋白质及多肽, 海参脂质, 海参皂苷等功效成分的研究, 确认了其在护肤 …

Characterization and heterologous expression of plasmalogen synthase MeHAD from Megasphaera elsdenii

F Zhang, Z Yang, Y Zhou, B Wang, Z Xie, N Yu… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Plasmalogens (Pls) are vinyl-ether bond-containing glycerophospholipids or glycosyl diradyl
glycerols, and are of great importance in the physiological functions and stability of cell …

VSP-2 attenuates secretion of inflammatory cytokines induced by LPS in BV2 cells by mediating the PPARγ/NF-κB signaling pathway

J Cui, L Xu, Y Sun, L Dai, Y Mo, K Yun, Y Chen… - Open Life …, 2024 - degruyter.com
Neuroinflammation, characterized by microglial activation and the subsequent secretion of
inflammatory cytokines, plays a pivotal role in neurodegenerative diseases and brain …

[PDF][PDF] Ginkgo Biloba Extract Containing Plasmalogen May Improve Brain Function Decline Including Brain Fog

S Kawakami, Y Tanaka, M Usui, S Iida, T Shirakawa… - 2024 - megajournalofcasereports.com
Deterioration of brain function, including brain fog, is currently becoming a serious problem
as it impairs daily life and quality of life. When it comes to decline in brain function …

Биохимическая и сигнальная функции плазмалогенов в норме и при различных заболеваниях

ОЮ Кытикова, ТП Новгородцева… - Вестник Российской …, 2023 - elibrary.ru
Плазмалогены (ПЛ)-это алкенилэфирные глицерофосфолипиды, выполняющие
множество физиологически важных функций в организме и обладающие …