Roles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis

U Förstermann, N Xia, H Li - Circulation research, 2017 - Am Heart Assoc
Major reactive oxygen species (ROS)–producing systems in vascular wall include NADPH
(reduced form of nicotinamide adenine dinucleotide phosphate) oxidase, xanthine oxidase …

Vascular smooth muscle cells and arterial stiffening: relevance in development, aging, and disease

P Lacolley, V Regnault, P Segers… - Physiological …, 2017 - journals.physiology.org
The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Clinical update: cardiovascular disease in diabetes mellitus: atherosclerotic cardiovascular disease and heart failure in type 2 diabetes mellitus–mechanisms …

CC Low Wang, CN Hess, WR Hiatt, AB Goldfine - Circulation, 2016 - Am Heart Assoc
Cardiovascular disease remains the principal cause of death and disability among patients
with diabetes mellitus. Diabetes mellitus exacerbates mechanisms underlying …

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

Y Kojima, JP Volkmer, K McKenna, M Civelek, AJ Lusis… - Nature, 2016 - nature.com
Atherosclerosis is the disease process that underlies heart attack and stroke. Advanced
lesions at risk of rupture are characterized by the pathological accumulation of diseased …

Essential oils of oregano: Biological activity beyond their antimicrobial properties

N Leyva-López, EP Gutiérrez-Grijalva… - Molecules, 2017 - mdpi.com
Essential oils of oregano are widely recognized for their antimicrobial activity, as well as
their antiviral and antifungal properties. Nevertheless, recent investigations have …

The dormant blood microbiome in chronic, inflammatory diseases

M Potgieter, J Bester, DB Kell… - FEMS microbiology …, 2015 - academic.oup.com
Blood in healthy organisms is seen as a 'sterile'environment: it lacks proliferating microbes.
Dormant or not-immediately-culturable forms are not absent, however, as intracellular …

[HTML][HTML] Antioxidative activity of high-density lipoprotein (HDL): Mechanistic insights into potential clinical benefit

F Brites, M Martin, I Guillas, A Kontush - BBA clinical, 2017 - Elsevier
Uptake of low-density lipoprotein (LDL) particles by macrophages represents a key step in
the development of atherosclerotic plaques, leading to the foam cell formation. Chemical …

The role of vascular smooth muscle cells in arterial remodeling: focus on calcification-related processes

A Jaminon, K Reesink, A Kroon… - International journal of …, 2019 - mdpi.com
Arterial remodeling refers to the structural and functional changes of the vessel wall that
occur in response to disease, injury, or aging. Vascular smooth muscle cells (VSMC) play a …

Plant polyphenols and their potential benefits on cardiovascular health: A review

I Iqbal, P Wilairatana, F Saqib, B Nasir, M Wahid… - Molecules, 2023 - mdpi.com
Fruits, vegetables, and other food items contain phytochemicals or secondary metabolites
which may be considered non-essential nutrients but have medicinal importance. These …

Endothelial–vascular smooth muscle cells interactions in atherosclerosis

M Li, M Qian, K Kyler, J Xu - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Atherosclerosis is a chronic progressive inflammatory process that can eventually lead to
cardiovascular disease (CVD). Despite available treatment, the prevalence of …