[HTML][HTML] Diversity matters: opportunities in the study of the genetics of psychotic disorders in low-and middle-income countries in Latin America

L Fonseca, BF Sena, N Crossley… - Brazilian journal of …, 2020 - SciELO Brasil
Lack of diversity regarding genetic and environmental backgrounds weakens the
generalization and clinical applicability of research findings on psychotic disorders. Notably …

[PDF][PDF] Genetic architecture of gene expression in European and African Americans: an eQTL mapping study in GENOA

L Shang, JA Smith, W Zhao, M Kho, ST Turner… - The American Journal of …, 2020 - cell.com
Most existing expression quantitative trait locus (eQTL) mapping studies have been focused
on individuals of European ancestry and are underrepresented in other populations …

Expanding the clinical relevance of the 5′-nucleotidase cN-II/NT5C2

LP Jordheim - Purinergic Signalling, 2018 - Springer
Purine metabolism is depending on a large amount of enzymes to ensure cellular
homeostasis. Among these enzymes, we have been interested in the 5′-nucleotidase cN-II …

The X factor: A robust and powerful approach to X‐chromosome‐inclusive whole‐genome association studies

B Chen, RV Craiu, LJ Strug, L Sun - Genetic epidemiology, 2021 - Wiley Online Library
The X‐chromosome is often excluded from genome‐wide association studies because of
analytical challenges. Some of the problems, such as the random, skewed, or no X …

[HTML][HTML] Genetic variants involved in bipolar disorder, a rough road ahead

G Orrù, MG Carta - Clinical practice and epidemiology in mental …, 2018 - ncbi.nlm.nih.gov
Background: Bipolar Disorder (BD), along with depression and schizophrenia, is one of the
most serious mental illnesses, and one of the top 20 causes of severe impairment in …

MicroRNA alterations in induced pluripotent stem cell-derived neurons from bipolar disorder patients: pathways involved in neuronal differentiation, axon guidance …

M Bame, MG McInnis, KS O'Shea - Stem cells and development, 2020 - liebertpub.com
Bipolar disorder (BP) is a complex psychiatric condition characterized by severe fluctuations
in mood for which underlying pathological mechanisms remain unclear. Family and twin …

HLA genetics in bipolar disorder

R Tamouza, J Oliveira, B Etain… - Acta Psychiatrica …, 2018 - Wiley Online Library
Objective Bipolar Disorder (BD) is characterized by deregulated adaptive immune
processes. Recent genome‐wide association studies (GWAS) implicate the major …

Parental warmth, stressful life events, and impulsivity: A gene–environment-wide interaction study.

X Wang, H Liu, Q He, C Chen, G Xue, Q Dong… - …, 2023 - psycnet.apa.org
Objective: Impulsivity is influenced by genetic, neural, and environmental factors, but no
study has examined how these factors work together to generate individual differences in …

TwinsMX: uncovering the basis of health and disease in the Mexican population

AV Leon-Apodaca, E Chiu-Han… - Twin Research and …, 2019 - cambridge.org
TwinsMX is a national twin registry in Mexico recently created with institutional support from
the Universidad Nacional Autónoma de México. It aims to serve as a platform to advance …

Genome‐wide association and replication studies for handedness in a Korean community‐based cohort

Y Song, D Lee, JE Choi, JW Lee… - Brain and Behavior, 2023 - Wiley Online Library
Introduction Handedness is a conspicuous characteristic in human behavior, with a
worldwide proportion of approximately 90% of people preferring to use the right hand for …