Mechanical stress from haemodynamic perturbations or interventional manipulation of
epicardial coronary atherosclerotic plaques with inflammatory destabilization can release …

During the past decade, our understanding of the pathophysiology of coronary artery
disease (CAD) has undergone a remarkable evolution. We review here how these advances …

Objective: To review our current understanding of the epidemiology and pathogenesis of
vein graft failure (VGF), give an overview of current preventive and interventional measures …

Background Carotid endarterectomy is more effective than medical management in the
prevention of stroke in patients with severe symptomatic or asymptomatic atherosclerotic …

Background Primary percutaneous coronary intervention (PCI) is effective in opening the
infarct-related artery in patients with myocardial infarction with ST-segment elevation …

Background—Heart failure treatment depends partly on the underlying cause of the disease.
We evaluated cardiovascular magnetic resonance (CMR) for the problem of differentiating …

The management of acute myocardial infarction continues to undergo major changes. Good
practice should be based on sound evidence derived from well-conducted clinical trials …

Non-ischaemic cardiomyopathies (NICMs) are chronic, progressive myocardial diseases
with distinct patterns of morphological, functional, and electrophysiological changes. In the …

In patients with stable CAD, PCI can be considered a valuable initial mode of
revascularization in all patients with objective large ischaemia in the presence of almost …

Background—A relatively simple, invasive method for quantitatively assessing the status of
the coronary microcirculation independent of the epicardial artery is lacking. Methods and …