Expansion of extracellular fluid volume is central to the pathophysiology of heart failure.
Increased extracellular fluid leads to elevated intracardiac filling pressures, resulting in a …

Longstanding hypertension ultimately leads to heart failure (HF), and, as a consequence
most patients with HF have a history of hypertension. Conversely, absence of hypertension …

Since the inception of the Canadian Cardiovascular Society heart failure (HF) guidelines in
2006, much has changed in the care for patients with HF. Over the past decade, the HF …

Heart failure (HF) is a major health-care problem and the prognosis of affected patients is
poor. HF often coexists with a number of comorbidities of which declining renal function is of …

Patients with type 2 diabetes mellitus have an increased risk for the development of cardiac
and other vascular events, heart failure (HF), and decline in renal function. After several …

Cardiovascular morbidity and mortality in patients with chronic kidney disease (CKD) is high,
and the presence of CKD worsens outcomes of cardiovascular disease (CVD). CKD is …

Pulmonary hypertension (PH) due to left heart disease, classified as group 2 according to
the Dana Point 2008 classification, is believed to be the most common cause of PH and is …

Patients with chronic kidney disease and end-stage renal disease are at 5-to 10-fold higher
risk for developing cardiovascular disease (CVD) than age-matched controls. Clinically …

Background Community-acquired pneumonia (CAP) is a leading cause of morbidity and
mortality. CAP can trigger acute cardiac events. We sought to determine the incidence of …

Combined dysfunction of the heart and the kidneys, which can be associated with
haemodynamic impairment, is classically referred to as cardiorenal syndrome (CRS) …