Overconsumption of Omega‐6 polyunsaturated fatty acids (PUFAs) versus deficiency of Omega‐3 PUFAs in modern‐day diets: the disturbing factor for their “balanced …

AH Mariamenatu, EM Abdu - Journal of lipids, 2021 - Wiley Online Library
Polyunsaturated fatty acids (PUFAs) contain≥ 2 double‐bond desaturations within the acyl
chain. Omega‐3 (n‐3) and Omega‐6 (n‐6) PUFAs are the two known important families in …

Associations among dietary omega‐3 polyunsaturated fatty acids, the gut microbiota, and intestinal immunity

Y Fu, Y Wang, H Gao, DH Li, RR Jiang… - Mediators of …, 2021 - Wiley Online Library
Omega‐3 polyunsaturated fatty acids (omega‐3 PUFAs), which are essential fatty acids that
humans should obtain from diet, have potential benefits for human health. In addition to …

Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance—A review

RK Saini, YS Keum - Life sciences, 2018 - Elsevier
Abstract Linoleic acid (LA)(n− 6) and α-linolenic acid (ALA)(n− 3) are essential fatty acids
(EFAs) as they cannot be synthesized by humans or other higher animals. In the human …

[HTML][HTML] The anti-inflammatory and antioxidant properties of n-3 PUFAs: Their role in cardiovascular protection

F Oppedisano, R Macrì, M Gliozzi, V Musolino… - Biomedicines, 2020 - mdpi.com
Polyunsaturated fatty acids (n-3 PUFAs) are long-chain polyunsaturated fatty acids with 18,
20 or 22 carbon atoms, which have been found able to counteract cardiovascular diseases …

[HTML][HTML] General Health Benefits and Pharmacological Activities of Triticum aestivum L.

S Moshawih, RNA Abdullah Juperi, GS Paneerselvam… - Molecules, 2022 - mdpi.com
Common wheat (Triticum aestivum), one of the world's most consumed cereal grains, is
known for its uses in baking and cooking in addition to its medicinal uses. As this plant's …

[HTML][HTML] Oxidative stress and non-alcoholic fatty liver disease: effects of omega-3 fatty acid supplementation

J Yang, M Fernández-Galilea, L Martínez-Fernández… - Nutrients, 2019 - mdpi.com
Aging is a complex phenomenon characterized by the progressive loss of tissue and organ
function. The oxidative-stress theory of aging postulates that age-associated functional …

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

A Kauppinen, T Suuronen, J Ojala, K Kaarniranta… - Cellular signalling, 2013 - Elsevier
Recent studies have indicated that the regulation of innate immunity and energy metabolism
are connected together through an antagonistic crosstalk between NF-κB and SIRT1 …

Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association

M Miller, NJ Stone, C Ballantyne, V Bittner, MH Criqui… - Circulation, 2011 - Am Heart Assoc
A long-standing association exists between elevated triglyceride levels and cardiovascular
disease*(CVD). 1, 2 However, the extent to which triglycerides directly promote CVD or …

Obesity and aging: Molecular mechanisms and therapeutic approaches

AL Santos, S Sinha - Ageing Research Reviews, 2021 - Elsevier
The epidemic of obesity is a major challenge for health policymakers due to its far-reaching
effects on population health and potentially overwhelming financial burden on healthcare …

[HTML][HTML] Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins*♦

JL Feldman, J Baeza, JM Denu - Journal of Biological Chemistry, 2013 - ASBMB
Mammalian sirtuins (SIRT1 through SIRT7) are members of a highly conserved family of
NAD+-dependent protein deacetylases that function in metabolism, genome maintenance …