Psoriasis is the result of uncontrolled keratinocyte proliferation, and its pathogenesis
involves the dysregulation of the immune system. The interplay among cytokines released …

Atopic dermatitis is a chronic, recurrent inflammatory skin disorder manifesting by
eczematous lesions and intense pruritus. Atopic dermatitis develops primarily as a result of …

Indolent systemic mastocytosis (ISM) is the most prevalent form of systemic mastocytosis.
Many patients with ISM suffer from mast cell (MC) mediator-related symptoms. In a small …

Background In recent years, biologics targeting key cytokines and Janus kinase (JAK)
inhibitors have demonstrated favorable efficacy and safety outcomes for atopic dermatitis …

The article entitled “Application of Janus Kinase Inhibitors in Atopic Dermatitis: An Updated
Systematic Review and Meta-Analysis of Clinical Trials” that belongs to the Special …

Janus kinase (JAK) refers to a family of tyrosine kinases that are involved in the production
of proinflammatory mediators in response to various extracellular signals. The JAK–signal …

Introduction Atopic dermatitis is one of the most prevalent chronic skin diseases. Topical
therapies continue to be the mainstay of treatment but are limited by noncompliance and …

Atopic dermatitis (AD) is a common relapsing inflammatory skin condition associated with a
high economic burden due to its chronicity and multitude of direct and indirect treatment …

Introduction Vitiligo is a chronic, autoimmune condition characterized by skin
depigmentation caused by inflammatory-mediated melanocyte degradation. Treatment of …

Background: Atopic dermatitis (AD) has a complex etiology that includes Th2 polarization,
which is accompanied by the cytokines IL4, IL-5, IL-13, and IL-31, as well as Th17 and Th22 …