Breast milk, a source of beneficial microbes and associated benefits for infant health

KE Lyons, CA Ryan, EM Dempsey, RP Ross, C Stanton - Nutrients, 2020 - mdpi.com
Human breast milk is considered the optimum feeding regime for newborn infants due to its
ability to provide complete nutrition and many bioactive health factors. Breast feeding is …

The multifaceted roles of breast milk antibodies

C Atyeo, G Alter - Cell, 2021 - cell.com
Neonates are born with an immature immune system and rely on the transfer of immunity
from their mothers. Maternal antibodies are transferred via the placenta and breast milk …

Prostate cancer reactivates developmental epigenomic programs during metastatic progression

MM Pomerantz, X Qiu, Y Zhu, DY Takeda, W Pan… - Nature …, 2020 - nature.com
Epigenetic processes govern prostate cancer (PCa) biology, as evidenced by the
dependency of PCa cells on the androgen receptor (AR), a prostate master transcription …

The mammary gland: basic structure and molecular signaling during development

SK Biswas, S Banerjee, GW Baker, CY Kuo… - International Journal of …, 2022 - mdpi.com
The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

Urine excretion, organ distribution, and placental transfer of 6PPD and 6PPD-quinone in mice and potential developmental toxicity through nuclear receptor pathways

HN Zhao, SP Thomas, MJ Zylka… - Environmental …, 2023 - ACS Publications
The rubber antioxidant 6PPD has gained significant attention due to its highly toxic
transformation product, 6PPD-quinone (6PPDQ). Despite their detection in urines of …

Mammary gland development: cell fate specification, stem cells and the microenvironment

JL Inman, C Robertson, JD Mott, MJ Bissell - Development, 2015 - journals.biologists.com
The development of the mammary gland is unique: the final stages of development occur
postnatally at puberty under the influence of hormonal cues. Furthermore, during the life of …

[HTML][HTML] Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing

K Bach, S Pensa, M Grzelak, J Hadfield… - Nature …, 2017 - nature.com
Characterising the hierarchy of mammary epithelial cells (MECs) and how they are
regulated during adult development is important for understanding how breast cancer …

Distinct stem cells contribute to mammary gland development and maintenance

A Van Keymeulen, AS Rocha, M Ousset, B Beck… - Nature, 2011 - nature.com
The mammary epithelium is composed of several cell lineages including luminal, alveolar
and myoepithelial cells. Transplantation studies have suggested that the mammary …

Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression

DS Micalizzi, SM Farabaugh, HL Ford - Journal of mammary gland biology …, 2010 - Springer
From the earliest stages of embryonic development, cells of epithelial and mesenchymal
origin contribute to the structure and function of developing organs. However, these …

Developmental stage and time dictate the fate of Wnt/β-catenin-responsive stem cells in the mammary gland

R Van Amerongen, AN Bowman, R Nusse - Cell stem cell, 2012 - cell.com
The mammary epithelium undergoes extensive growth and remodeling during pregnancy,
suggesting a role for stem cells. Yet their origin, identity, and behavior in the intact tissue …