Background A systematic understanding of how multimorbidity has been constructed and
measured is unavailable. This review aimed to examine the definition and measurement of …

This review discusses the interplay between multimorbidity (ie co‐occurrence of more than
one chronic health condition in an individual) and functional impairment (ie limitations in …

The population of aged individuals is increasing worldwide and this has significant health
and socio-economic implications. Clinical and experimental studies on aging have …

Introduction We investigate dementia risk in older adults with different disease patterns and
explore the role of inflammation and apolipoprotein E (APOE) genotype. Methods A total of …

Importance Longitudinal associations between comorbid depression and anxiety with the
accumulation of chronic illnesses are unclear, and questions remain about the contributions …

Objective To study the association between bilateral oophorectomy and the rate of
accumulation of multimorbidity. Patients and Methods In this historical cohort study, the …

Over the past three decades, considerable effort has been dedicated to quantifying the pace
of ageing yet identifying the most essential metrics of ageing remains challenging due to …

Multimorbidity, the presence of 1+ chronic condition in an individual, remains one of the
greatest challenges to health on a global scale. Although the prevalence of multimorbidity …

To define metrics of phenotypic aging, it is essential to identify biological and environmental
factors that influence the pace of aging. Previous attempts to develop aging metrics were …

Objectives To assess the association between chronic physical conditions and
multimorbidity and mild cognitive impairment (MCI) in low‐and middle‐income countries …