[HTML][HTML] Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV
CW Chao, KR Sprouse, MC Miranda, NJ Catanzaro… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic betacoronavirus
that causes severe and often lethal respiratory illness in humans. The MERS-CoV spike (S) …
that causes severe and often lethal respiratory illness in humans. The MERS-CoV spike (S) …
[HTML][HTML] Designed mosaic nanoparticles enhance cross-reactive immune responses in mice
Using computational methods, we designed 60-mer nanoparticles displaying SARS-like
betacoronavirus (sarbecovirus) receptor-binding domains (RBDs) by (i) creating RBD …
betacoronavirus (sarbecovirus) receptor-binding domains (RBDs) by (i) creating RBD …
Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques
M Mandolesi, H Das, L de Vries, Y Yang, C Kim… - 2024 - researchsquare.com
The continued evolution of SARS-CoV-2 underscores the need to understand qualitative
aspects of the humoral immune response elicited by spike immunization. Here, we …
aspects of the humoral immune response elicited by spike immunization. Here, we …