Background The utility of longitudinal, circumferential, and radial strain and strain rate in
determining prognosis in chronic heart failure is not well established. Methods and Results …

Aims Few data are available on the extent and prognostic value of reverse left ventricular
remodelling (r-LVR) after ST-elevation acute myocardial infarction (STEMI). We sought to …

Background—Expansion of an acute myocardial infarction predicts progressive left
ventricular (LV) dilatation, functional deterioration, and early death. This study tests the …

Background—Incomplete suppression of the renin-angiotensin system during long-term
ACE inhibition may contribute to symptomatic deterioration in patients with severe …

Because of the increasing number of pharmacologic strategies available for treatment of
heart failure (HF), the time has come to reassess the adequacy of end points used to …

Background—Previous studies suggest that angiotensin II (Ang II) upregulates the
expression of tumor necrosis factor (TNF) in nonmyocyte cell types; however, the effect of …

Chronic ischaemic mitral regurgitation (CIMR) remains one of the most complex and
unresolved aspects in the management of ischaemic heart disease. This review provides an …

Background The development of ischemic mitral regurgitation (MR) after myocardial
infarction may impose hemodynamic load during a period of active left ventricular …

Abstract Background In the REPAIR-AMI trial, intracoronary infusion of bone marrow-derived
cells (BMCs) was associated with a significantly greater recovery of contractile function in …

Aims Ultrasound-targeted microbubble destruction (UTMD) uses ultrasound energy to
selectively deliver genes into the myocardium using plasmids conjugated to microbubbles …