Mur enzymes serve as critical molecular devices for the synthesis of UDP-MurNAc-
pentapeptide, the main building block of bacterial peptidoglycan polymer. These enzymes …

Feruloyl Methane (FM) is a common impurity in Synthetic Curcumin (SC) that affects its purity
and potency. The identification and quantification of FM is crucial to ensure the quality and …

In this study, we report the design, synthesis, computational and experimental evaluation of
the antimicrobial activity, as well as docking studies of new 5-methylthiazole based …

Despite the greatest achievement in the development of anti-inflammatory agents in the last
two decades, the current clinical drugs suffer from a variety of complications in community …

The search for new antimicrobial agents is greater than ever due to the perpetual threat of
multidrug resistance in known pathogens and the relentless emergence of new infections. In …

Despite great efforts in the discovery of antifungal drugs in the last two decades, the
increasing incidence of infectious diseases from diverse pathogenic fungi threatens public …

Alteration of insect growth regulators by the action of inhibitors is becoming an attractive
strategy to combat disease-transmitting insects. In the present study, we investigated the …

Malaria is one of the most known vector-borne diseases caused by female Anopheles
mosquito bites. According to WHO, about 247 million cases of malaria and 619,000 deaths …

Major obstacles faced by the use of nonsteroidal anti-inflammatory drugs (NSAID) are their
gastrointestinal toxicity induced by non-selective inhibition of both cyclooxygenases (COX) 1 …

Background: Tuberculosis remains one of the most deadly infectious diseases worldwide
due to the emergence of multi-drug resistance (MDR) and extensively drug resistance (XDR) …