Replacing in vivo with in vitro studies can increase sustainability in the development of
medicines. This principle has already been applied in the biowaiver approach based on the …

Climate change and the destruction of ecosystems by human activities are among the
greatest challenges of the 21st century and require urgent action. Health care activities …

Background Recruiting participants to clinical trials is an ongoing challenge, and relatively
little is known about what recruitment strategies lead to better recruitment. Recruitment …

Healthcare provision has a significant climate impact and, conversely, the climate is a
determinant of population health. Research is underway to quantify the emissions from …

In this paper we argue the need to reimagine research ethics frameworks to include notions
of environmental sustainability. While there have long been calls for health care ethics …

Background Human activities have changed the environment so profoundly over the past
two centuries that human-induced climate change is now posing serious health-related …

Introduction Participant recruitment to clinical trials is often sub-optimal. Decentralized
clinical trials have the potential to address challenges in traditional site-based clinical trial …

Introduction All economic sectors including the service sector, along with healthcare,
education and research, need to reduce their greenhouse gas emissions to limit global …

Objectives To quantify the carbon footprint from a sample of pharma industry sponsored
phase III trials. To develop an approach that can readily be applied to future trials by …

In recent years the terms time and financial toxicities have entered the vocabulary of cancer
care. We would like to introduce another toxicity: climate toxicity. Climate toxicity is a double …