Metabolic interactions between disease-transmitting vectors and their microbiota

X Song, Z Zhong, L Gao, BL Weiss, J Wang - Trends in Parasitology, 2022 - cell.com
Disease-transmitting vectors are living organisms that pass infectious agents from one
animal/human to another. The epidemiologically important vectors are usually …

The tick-borne pathogens: an overview of China's situation

Y Luan, J Gou, D Zhong, L Ma, C Yin, M Shu, G Liu… - Acta Parasitologica, 2023 - Springer
Background Ticks are important medical arthropods that can transmit hundreds of
pathogens, such as parasites, bacteria, and viruses, leading to serious public health …

A fluorescently-tagged tick kinin neuropeptide triggers peristalsis and labels tick midgut muscles

JR Hernandez, C Xiong, PV Pietrantonio - Scientific Reports, 2024 - nature.com
Ticks are blood-feeding arthropods that require heme for their successful reproduction.
During feeding they also acquire pathogens that are subsequently transmitted to humans …

Bacterial reprogramming of tick metabolism impacts vector fitness and susceptibility to infection

S Samaddar, A Rolandelli, AJ O'Neal… - Nature …, 2024 - nature.com
Arthropod-borne pathogens are responsible for hundreds of millions of infections in humans
each year. The blacklegged tick, Ixodes scapularis, is the predominant arthropod vector in …

Interactions between ticks and lyme disease spirochetes

U Pal, C Kitsou, D Drecktrah, OB Yas… - Current issues in molecular …, 2021 - mdpi.com
Borrelia burgdorferi sensu lato causes Lyme borreliosis in a variety of animals and humans.
These atypical bacterial pathogens are maintained in a complex enzootic life cycle that …

Rickettsial pathogen perturbs tick circadian gene to infect the vertebrate host

S Khanal, V Taank, JF Anderson, H Sultana… - International Journal of …, 2022 - mdpi.com
Ixodes scapula ris is a medically important tick that transmits several microbes to humans,
including rickettsial pathogen Anaplasma phagocytophilum. In nature, these ticks encounter …

De novo assembly and annotation of the Amblyomma hebraeum tick midgut transcriptome response to Ehrlichia ruminantium infection

D Omondi, E Zweygarth, E Murungi… - PLOS Neglected …, 2023 - journals.plos.org
The South African bont tick Amblyomma hebraeum is a hematophagous vector for the
heartwater disease pathogen Ehrlichia ruminantium in southern Africa. During feeding, the …

The arginine deaminase system plays distinct roles in Borrelia burgdorferi and Borrelia hermsii

CL Richards, SJ Raffel, S Bontemps-Gallo… - PLoS …, 2022 - journals.plos.org
Borrelia species are amino acid auxotrophs that utilize di-and tri-peptides obtained through
their oligopeptide transport system to supply amino acids for replicative growth during their …

Antibody-blocking of a tick transporter impairs Anaplasma phagocytophilum colonization in Haemaphysalis longicornis ticks

P Namjoshi, DM Lubembe, H Sultana… - Scientific Reports, 2024 - nature.com
The invasive Asian longhorned tick Haemaphysalis longicornis that vectors and transmits
several animal pathogens is significantly expanding in the United States. Recent studies …

Enlisting the Ixodes scapularis Embryonic ISE6 Cell Line to Investigate the Neuronal Basis of Tick—Pathogen Interactions

L Mateos-Hernández, N Pipová, E Allain, C Henry… - Pathogens, 2021 - mdpi.com
Neuropeptides are small signaling molecules expressed in the tick central nervous system,
ie, the synganglion. The neuronal-like Ixodes scapularis embryonic cell line, ISE6, is an …