Cancer is the second leading cause of death globally, trailing only heart disease. In the
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …

Ubiquitination is a reversible post-translational modification based on the chemical addition
of ubiquitin to proteins with regulatory effects on various signaling pathways. Ubiquitination …

The dismal prognosis of pancreaticobiliary malignancies is mainly attributed to the extremely
difficult detection of early‐stage lesions, including intraepithelial neoplasia. To improve …

Rapid advancements in high-throughput single-cell RNA-seq (scRNA-seq) technologies
and experimental protocols have led to the generation of vast amounts of genomic data that …

Hepatic stellate cells (HSC) are the source of extracellular matrix (ECM) whose
overproduction leads to fibrosis, a condition that impairs liver functions in chronic liver …

Computational modeling and analysis of biomolecular network models annotated with
cancer patient-specific multi-omics data can enable the development of personalized …