Contemporary natural history of bicuspid aortic valve disease: a systematic review

A Masri, LG Svensson, BP Griffin, MY Desai - Heart, 2017 - heart.bmj.com
We performed a systematic review of the current state of the literature regarding the natural
history and outcomes of bicuspid aortic valve (BAV). PubMed and the reference lists of the …

Pathogenic mechanisms of bicuspid aortic valve aortopathy

NM Yassine, JT Shahram, SC Body - Frontiers in physiology, 2017 - frontiersin.org
Bicuspid aortic valve (BAV) is the most common congenital valvular defect and is associated
with ascending aortic dilation (AAD) in a quarter of patients. AAD has been ascribed both to …

Update in biomolecular and genetic bases of bicuspid aortopathy

A Junco-Vicente, Á del Río-García, M Martín… - International journal of …, 2021 - mdpi.com
Bicuspid aortic valve (BAV) associated with aortopathy is the most common congenital heart
disease in the general population. Far from being a simple harmless valve malformation, it …

[HTML][HTML] The aortic root does not dilate over time after replacement of the aortic valve and ascending aorta in patients with bicuspid or tricuspid aortic valves

SK Hui, CPS Fan, S Christie, CM Feindel… - The Journal of thoracic …, 2018 - Elsevier
Objective Whether the aortopathy associated with bicuspid aortic valve (BAV) disease
occurs secondary to genetic or hemodynamic factors remains controversial. In this article we …

Enlightening the association between bicuspid aortic valve and aortopathy

F Sophocleous, EG Milano, G Pontecorboli… - Journal of …, 2018 - mdpi.com
Bicuspid aortic valve (BAV) patients have an increased incidence of developing aortic
dilation. Despite its importance, the pathogenesis of aortopathy in BAV is still largely …

The predictive role of plasma biomarkers in the evolution of aortopathies associated with congenital heart malformations

A Făgărășan, MO Săsăran - International Journal of Molecular Sciences, 2022 - mdpi.com
Dilatation of the aorta is a constantly evolving condition that can lead to the ultimate life-
threatening event, acute aortic dissection. Recent research has tried to identify quantifiable …

Segmental aortic stiffness in patients with bicuspid aortic valve compared with first-degree relatives

G Goudot, T Mirault, A Rossi, S Zarka, J Albuisson… - Heart, 2019 - heart.bmj.com
Aims To compare the stiffness index in patients with bicuspid aortic valve (BAV) with first-
degree relatives at each segment of the thoracic ascending aorta and to compare segmental …

Bicuspid aortic valve morphology and its impact on aortic diameters—A systematic review with meta‐analysis and meta‐regression

D Miśkowiec, P Lipiec, E Szymczyk… - …, 2018 - Wiley Online Library
Aim To evaluate the impact of the 2 most common bicuspid aortic valve (BAV) morphology
patterns [right‐left (RL) vs right‐noncoronary (RN) cusp fusion] on the aortic diameters and …

Valve disease and aortopathy associations of bicuspid aortic valve phenotypes differ between men and women

C Granath, SA Mohamed, C Olsson, M Grattan… - Open …, 2021 - openheart.bmj.com
Objective Determine whether associations between bicuspid aortic valve (BAV) phenotypes,
valve disease and aortopathy differ between sexes. Methods 1045 patients with BAV (76.0 …

[HTML][HTML] Navigating the challenges of bicuspid aortic valve-aortopathy

SG Kanagala, A Sawhney, K Parikh… - … Cardiology Science & …, 2023 - ncbi.nlm.nih.gov
Bicuspid aortic valve (BAV) is a congenital heart defect that affects 0.5–2% of the general
population with familial predominance. The modifications in hemodynamics and structure …