Diarylpentanoids with antitumor activity: A critical review of structure-activity relationship studies

J Moreira, L Saraiva, MM Pinto, H Cidade - European Journal of Medicinal …, 2020 - Elsevier
Diarypentanoids are commonly considered as monocarbonyl analogues of curcumin. Since
the discovery of this compound in 1962, twenty one diarylpentanoids have been isolated …

[HTML][HTML] Serum albumin binding studies on antiproliferative cyclic C5-curcuminoid derivatives using spectroscopic methods and molecular modelling

L Tyukodi, BZ Zsidó, C Hetényi, T Kőszegi… - Journal of Molecular …, 2023 - Elsevier
Cyclic C5-curcuminoid derivatives are synthetic analogues of the natural product curcumin
possessing diverse pharmacological potential. We described earlier that some of the cyclic …

BP-M345 as a Basis for the Discovery of New Diarylpentanoids with Promising Antimitotic Activity

J Moreira, PMA Silva, E Castro, L Saraiva… - International Journal of …, 2024 - mdpi.com
Recently, the diarylpentanoid BP-M345 (5) has been identified as a potent in vitro growth
inhibitor of cancer cells, with a GI50 value between 0.17 and 0.45 µM, showing low toxicity in …

Hemicurcuminoids (1-styryl-1, 3-diketones)–valuable multi-faceted building blocks for organic synthesis

NS Zimnitskiy, VY Korotaev, AY Barkov… - New Journal of …, 2023 - pubs.rsc.org
For the first time, a review has been conducted on the methods for the synthesis, as well as
on the chemical, physical and biological properties, of 5-arylpent-4-ene-1, 3-diones …

PHMH, a diarylheptanoid from Alpinia officinarum attenuates VEGF-induced angiogenesis via inhibition of the VEGFR-2 signaling pathway

L Hu, W Huang, Y Ding, M Liu, M Wang, Y Wang… - Food & function, 2019 - pubs.rsc.org
The rhizome of Alpinia officinarum Hance, a popular spice used as a condiment in China
and Europe, has various reported bioactivities, including anticancer, anti-inflammatory and …

[PDF][PDF] A New Diarylbenzophenone from Selaginella tamariscina

W Chen, Y Peng, W Huang, L Zhou, X Quan, Q Zhao… - Rec. Nat. Prod, 2020 - acgpubs.org
A new diarylbenzophenone, namely selagibenzophenone C (1), along with 1, 3-di-p-
hydroxyphenyl-4-penten-1-one,(2) and unciflavone E (3) were isolated from Selaginella …

8-8'-and 8-7'-Norlignan Biosynthesis Roadmap

LB Davin, NG Lewis - The Lignan Handbook, 2022 - taylorfrancis.com
As for natural product classes (eg terpenoids, alkaloids) the prefix nor-that is used in lignan
phytochemical descriptions depicts loss or removal of a single carbon functionality …

Synthesis of alnustone-like diarylpentanoids via a 4+ 1 strategy and assessment of their potential anticancer activity

N Çelebioğlu, ÖÖ Tozlu, H Türkez… - Turkish Journal of …, 2023 - journals.tubitak.gov.tr
Abstract Twelve compounds with a 1, 5-diaryl-1-penten-3-one structure were synthesized
and their cytotoxic activities were evaluated. The 1, 5-diaryl-1-penten-3-one compounds …

[PDF][PDF] Curcuma kwangsiensis extracts produced antioxidant effects against injury induced by H2O2 on PC12 cells

J Liu, L Zhang, J Zhang, B Li, M Zhang - Rec Nat Prod, 2019 - acgpubs.org
The radix of Curcuma kwangsiensis SG Lee & CF Liang (Zingiberaceae) is a traditional
medicine in China, and used for treating qi stagnation and blood stasis. Previous chemical …

[PDF][PDF] Phytochemistry of Dais cotinifolia L.

BB Danca - 2018 - core.ac.uk
Many plant-derived secondary metabolites have interesting biological activities and some
plant compounds such as artemisinin (antimalarial) and vincristine (anticancer agent) are …