Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …

Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

The amyloid cascade hypothesis: an updated critical review

KP Kepp, NK Robakis, PF Høilund-Carlsen, SL Sensi… - Brain, 2023 - academic.oup.com
Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Nanocatalytic medicine

B Yang, Y Chen, J Shi - Advanced materials, 2019 - Wiley Online Library
Catalysis and medicine are often considered as two independent research fields with their
own respective scientific phenomena. Promoted by recent advances in nanochemistry, large …

The role of copper homeostasis in brain disease

Y An, S Li, X Huang, X Chen, H Shan… - International journal of …, 2022 - mdpi.com
In the human body, copper is an important trace element and is a cofactor for several
important enzymes involved in energy production, iron metabolism, neuropeptide activation …

Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review

C Zhao, KP Rakesh, L Ravidar, WY Fang… - European journal of …, 2019 - Elsevier
Sulfur (S VI) based moieties, especially, the sulfonyl or sulfonamide based analogues have
showed a variety of pharmacological properties, and its derivatives propose a high degree …

Development of multifunctional molecules as potential therapeutic candidates for Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis in the …

MG Savelieff, G Nam, J Kang, HJ Lee, M Lee… - Chemical …, 2018 - ACS Publications
Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

What are heavy metals? Long-standing controversy over the scientific use of the term 'heavy metals'–proposal of a comprehensive definition

H Ali, E Khan - Toxicological & Environmental Chemistry, 2018 - Taylor & Francis
The term 'heavy metals' is commonly used in the environmental literature to refer to metals
and metalloids associated with environmental pollution, toxicity and adverse effects on biota …

Fluorescent diagnostic probes in neurodegenerative diseases

J Zhou, P Jangili, S Son, MS Ji, M Won… - Advanced …, 2020 - Wiley Online Library
Neurodegenerative diseases are debilitating disorders that feature progressive and
selective loss of function or structure of anatomically or physiologically associated neuronal …