Electrophysiological properties of pluripotent human and mouse embryonic stem cells

K Wang, T Xue, SY Tsang, R Van Huizen… - Stem Cells, 2005 - academic.oup.com
Pluripotent embryonic stem cells (ESCs) possess promising potential for cell‐based
therapies, but their electrophysiological properties have not been characterized. Here we …

Alu Sequences in Undifferentiated Human Embryonic Stem Cells Display High Levels of A-to-I RNA Editing

S Osenberg, N Paz Yaacov, M Safran, S Moshkovitz… - PLoS one, 2010 - journals.plos.org
Adenosine to Inosine (A-to-I) RNA editing is a site-specific modification of RNA transcripts,
catalyzed by members of the ADAR (Adenosine Deaminase Acting on RNA) protein family …

The International Stem Cell Initiative: toward benchmarks for human embryonic stem cell research

Steering Committee of the International Stem Cell … - Nature …, 2005 - nature.com
The International Stem Cell Initiative: toward benchmarks for human embryonic stem cell
research | Nature Biotechnology Skip to main content Thank you for visiting nature.com. You are …

Basic fibroblast growth factor and its receptors in human embryonic stem cells.

P Dvorak, A Hampl - Folia histochemica et Cytobiologica, 2005 - journals.viamedica.pl
Human embryonic stem cells (hESCs) are pluripotent stem cells with long-lasting capacity to
self-renew and differentiate into various cell types of endodermal, ectodermal or …

[HTML][HTML] Transcriptome analysis of early organogenesis in human embryos

H Fang, Y Yang, C Li, S Fu, Z Yang, G Jin, K Wang… - Developmental cell, 2010 - cell.com
Genome-wide expression analysis of embryonic development provides information that is
useful in a variety of contexts. Here, we report transcriptome profiles of human early embryos …

Size of the embryoid body influences chondrogenesis of mouse embryonic stem cells

JM Messana, NS Hwang, J Coburn… - Journal of tissue …, 2008 - Wiley Online Library
For applications in tissue engineering and regenerative medicine, embryonic stem cells
(ESCs) are commonly pre‐differentiated in the form of embryoid bodies (EBs). The …

Differentiation of neural lineage cells from human pluripotent stem cells

PH Schwartz, DJ Brick, AE Stover, JF Loring, FJ Müller - Methods, 2008 - Elsevier
Human pluripotent stem cells have the unique properties of being able to proliferate
indefinitely in their undifferentiated state and to differentiate into any somatic cell type. These …

Clonal analysis of human embryonic stem cell differentiation into teratomas

B Blum, N Benvenisty - Stem Cells, 2007 - academic.oup.com
Differentiation of human embryonic stem cells (HESCs) can be studied in vivo through the
induction of teratomas in immune-deficient mice. Cells within the teratomas differentiate into …

Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal

Y Mayshar, E Rom, I Chumakov, A Kronman… - Stem Cells, 2008 - academic.oup.com
Human embryonic stem cells (HESCs) are unique in their capacity to self-renew while
remaining pluripotent. This undifferentiated state must be actively maintained by secreted …

The embryonic stem cell test combined with toxicogenomics as an alternative testing model for the assessment of developmental toxicity

DAM van Dartel, AH Piersma - Reproductive toxicology, 2011 - Elsevier
One of the most studied in vitro alternative testing methods for identification of
developmental toxicity is the embryonic stem cell test (EST). Although the EST has been …