Interpreting population-and family-based genome-wide association studies in the presence of confounding
A central aim of genome-wide association studies (GWASs) is to estimate direct genetic
effects: the causal effects on an individual's phenotype of the alleles that they carry …
effects: the causal effects on an individual's phenotype of the alleles that they carry …
Wrestling with social and behavioral genomics: risks, potential benefits, and ethical responsibility
In this consensus report by a diverse group of academics who conduct and/or are concerned
about social and behavioral genomics (SBG) research, the authors recount the often‐ugly …
about social and behavioral genomics (SBG) research, the authors recount the often‐ugly …
Genetic associations with parental investment from conception to wealth inheritance in six cohorts
Genetic inheritance is not the only way parents' genes may affect children. It is also possible
that parents' genes are associated with investments into children's development. We …
that parents' genes are associated with investments into children's development. We …
Why we need families in genomic research on developmental psychopathology
Background Fundamental questions about the roles of genes, environments, and their
interplay in developmental psychopathology have traditionally been the domain of twin and …
interplay in developmental psychopathology have traditionally been the domain of twin and …
[HTML][HTML] The next 10 years of behavioural genomic research
R Plomin - JCPP advances, 2022 - ncbi.nlm.nih.gov
Background The explosion caused by the fusion of quantitative genetics and molecular
genetics will transform behavioural genetic research in child and adolescent psychology …
genetics will transform behavioural genetic research in child and adolescent psychology …
Conventional twin studies overestimate the environmental differences between families relevant to educational attainment
Estimates of shared environmental influence on educational attainment (EA) using the
Classical Twin Design (CTD) have been enlisted as genetically sensitive measures of …
Classical Twin Design (CTD) have been enlisted as genetically sensitive measures of …
[HTML][HTML] Luck, lottery, or legacy? The problem of confounding. A reply to Harden
G Coop, M Przeworski - Evolution; international journal of organic …, 2022 - ncbi.nlm.nih.gov
In Coop and Przeworski (2022), we argue that Harden (2021) misinterprets findings from
genome-wide association studies (GWAS) of educational attainment and overstates their …
genome-wide association studies (GWAS) of educational attainment and overstates their …
[HTML][HTML] Estimation of indirect genetic effects and heritability under assortative mating
AS Young - bioRxiv, 2023 - ncbi.nlm.nih.gov
Both direct genetic effects (effects of alleles in an individual on that individual) and indirect
genetic effects—effects of alleles in an individual (eg parents) on another individual (eg …
genetic effects—effects of alleles in an individual (eg parents) on another individual (eg …
Dissecting the polygenic contribution of attention-deficit/hyperactivity disorder and autism spectrum disorder on school performance by their relationship with …
J Cabana-Domínguez, R Bosch, M Soler Artigas… - Molecular …, 2024 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are
strongly associated with educational attainment (EA), but little is known about their genetic …
strongly associated with educational attainment (EA), but little is known about their genetic …
Genetic nurture in educational attainment
Health is strongly and positively correlated with education, which is one of many reasons to
better understand the determinants of education. In this paper, we test for a specific type of …
better understand the determinants of education. In this paper, we test for a specific type of …