Acting on the cytokine cascade is key to preventing disease progression and death in
hospitalised patients with COVID-19. Among anti-cytokine therapies, interleukin (IL)-6 …

Severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection leads to the
development of coronavirus disease 2019 (COVID-19), which causes endothelial …

Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …

The microRNA, miR-155 regulates both adaptive and innate immune responses. In viral
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …

Coronavirus disease 2019 (COVID-19) has caused a crisis to global public health since its
outbreak at the end of 2019. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of
respiratory and cardiovascular diseases, known as coronavirus disease 2019 (COVID-19) …

Due to the paucity of longitudinal molecular studies of COVID-19, particularly those covering
the early stages of infection (Days 1-8 symptom onset), our understanding of host response …

Simple Summary Children with a COVID-19 infection are at risk of developing a novel
syndrome called multisystem inflammatory syndrome in children (MIS-C). This disease state …

Coronavirus disease 2019 (COVID-19) was first reported in Wuhan, China, in late December
2019. Since then, COVID-19 has spread rapidly worldwide and was declared a global …

The JAK-STAT pathway is a crucial cellular signaling cascade, including an intricate network
of Protein–protein interactions (PPIs) responsible for its regulation. It mediates the activities …