NMR spectroscopic windows on the systemic effects of SARS-CoV-2 infection on plasma lipoproteins and metabolites in relation to circulating cytokines

S Lodge, P Nitschke, T Kimhofer… - Journal of Proteome …, 2021 - ACS Publications
To investigate the systemic metabolic effects of SARS-CoV-2 infection, we analyzed 1H
NMR spectroscopic data on human blood plasma and co-modeled with multiple plasma …

Infection of lung megakaryocytes and platelets by SARS-CoV-2 anticipate fatal COVID-19

A Zhu, F Real, C Capron, AR Rosenberg… - Cellular and Molecular …, 2022 - Springer
Abstract SARS-CoV-2, although not being a circulatory virus, spread from the respiratory
tract resulting in multiorgan failures and thrombotic complications, the hallmarks of fatal …

Role of CCL2/CCR2 axis in the pathogenesis of COVID-19 and possible Treatments: All options on the Table

M Ranjbar, A Rahimi, Z Baghernejadan… - International …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

Predictive factors for a severe course of COVID‐19 infection in myasthenia gravis patients with an overall impact on myasthenic outcome status and survival

M Jakubikova, M Týblová, A Tesař… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Myasthenia gravis (MG) patients could be a vulnerable group in
the pandemic era of coronavirus 2019 (COVID‐19) mainly due to respiratory muscle …

Bioengineered neutrophil extinguisher targets cascade immune pathways of macrophages for alleviating cytokine storm in pneumonia

A Zhou, K Chen, Y Gao, X Zhou, Z Tian, W Chen… - ACS …, 2023 - ACS Publications
Cytokine storm is a common complication of COVID-19 pneumonia and has been proven to
contribute to high mortality rates. However, current treatment approaches exhibit limited …

[HTML][HTML] NLRP3 inflammasome activation in COVID-19: an interlink between risk factors and disease severity

S Amin, S Aktar, MM Rahman, MMH Chowdhury - Microbes and infection, 2022 - Elsevier
NLRP3 inflammasome is a critical immune component that plays a crucial role in mounting
innate immune responses. The deleterious effects of inflammasome activation have been …

Severe COVID-19 and sepsis: immune pathogenesis and laboratory markers

MM Zafer, HA El-Mahallawy, HM Ashour - Microorganisms, 2021 - mdpi.com
The ongoing outbreak of the novel coronavirus disease 2019 (COVID-19), induced by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has taken a significant toll …

Targeting Inflammasome activation in viral infection: a therapeutic solution?

CH Deng, TQ Li, W Zhang, Q Zhao, Y Wang - Viruses, 2023 - mdpi.com
Inflammasome activation is exclusively involved in sensing activation of innate immunity and
inflammatory response during viral infection. Accumulating evidence suggests that the …

The diagnostic and therapeutic potential of galectin-3 in cardiovascular diseases

G Sygitowicz, A Maciejak-Jastrzębska, D Sitkiewicz - Biomolecules, 2021 - mdpi.com
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …

Cis-acting lnc-Cxcl2 restrains neutrophil-mediated lung inflammation by inhibiting epithelial cell CXCL2 expression in virus infection

S Liu, J Liu, X Yang, M Jiang, Q Wang… - Proceedings of the …, 2021 - National Acad Sciences
Chemokine production by epithelial cells is important for neutrophil recruitment during viral
infection, the appropriate regulation of which is critical for restraining inflammation and …