Coronil, a tri-herbal formulation, attenuates spike-protein-mediated SARS-CoV-2 viral entry into human alveolar epithelial cells and pro-inflammatory cytokines …

A Balkrishna, S Haldar, H Singh, P Roy… - Journal of …, 2021 - Taylor & Francis
Purpose: Coronil is a tri-herbal formulation containing extracts from Withania somnifera,
Tinospora cordifolia, and Ocimum sanctum. Recently, it was shown that Coronil rescued …

Impaired cytotoxic response in PBMCs from patients with COVID-19 admitted to the ICU: biomarkers to predict disease severity

L Vigon, D Fuertes, J Garcia-Perez, M Torres… - Frontiers in …, 2021 - frontiersin.org
Infection by novel coronavirus SARS-CoV-2 causes different presentations of COVID-19 and
some patients may progress to a critical, fatal form of the disease that requires their …

Emerging role of kinin B1 receptor in persistent neuroinflammation and neuropsychiatric symptoms in mice following recovery from SARS-CoV-2 infection

S Sriramula, D Theobald, RU Parekh, SM Akula… - Cells, 2023 - mdpi.com
Evidence suggests that patients with long COVID can experience neuropsychiatric,
neurologic, and cognitive symptoms. However, these clinical data are mostly associational …

A deep look into COVID-19 severity through dynamic changes in blood cytokine levels

DA Kleymenov, EN Bykonia, LI Popova… - Frontiers in …, 2021 - frontiersin.org
An excessive inflammatory response to SARS-CoV-2 is thought to be a major cause of
disease severity and mortality in patients with COVID-19. Longitudinal analysis of cytokine …

SARS-CoV-2 early infection signature identified potential key infection mechanisms and drug targets

Y Li, A Duche, MR Sayer, D Roosan, FG Khalafalla… - BMC genomics, 2021 - Springer
Background The ongoing COVID-19 outbreak has caused devastating mortality and posed a
significant threat to public health worldwide. Despite the severity of this illness and 2.3 …

[HTML][HTML] Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses

CA Beaudoin, AR Jamasb, AF Alsulami… - Computational and …, 2021 - Elsevier
Viruses often encode proteins that mimic host proteins in order to facilitate infection. Little
work has been done to understand the potential mimicry of the SARS-CoV-2, SARS-CoV …

Neuron-specific enolase serum levels in COVID-19 are related to the severity of lung injury

E Cione, A Siniscalchi, P Gangemi, L Cosco… - PLoS …, 2021 - journals.plos.org
The multifunctional role of neuron-specific enolase (NSE) in lung diseases is well
established. As the lungs are greatly affected in COVID-19, we evaluated serum NSE levels …

Potential biomarkers for the early prediction of SARS-COV-2 disease outcome

V Mariappan, PS Manoharan, R Pajanivel… - Microbial …, 2021 - Elsevier
The current pandemic due to the fast spreading of SARS-CoV-2 infection has caused severe
impairment in health, social, economic, scientific, and medical sectors across the globe …

Recent advances in antibody‐based immunotherapy strategies for COVID‐19

A Esmaeilzadeh, S Rostami… - Journal of cellular …, 2021 - Wiley Online Library
The emergence of a new acute respiratory syndrome Coronavirus 2 (SARS‐CoV‐2), the
cause of the 2019‐nCOV disease (COVID‐19), has caused a pandemic and a global health …

A replicon RNA vaccine can induce durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

MA O'Connor, DW Hawman, K Meade-White… - Plos …, 2023 - journals.plos.org
The global SARS-CoV-2 pandemic prompted rapid development of COVID-19 vaccines.
Although several vaccines have received emergency approval through various public health …