IFP35 as a promising biomarker and therapeutic target for the syndromes induced by SARS-CoV-2 or influenza virus

Y Yu, N Xu, Q Cheng, F Deng, M Liu, A Zhu, YQ Min… - Cell Reports, 2021 - cell.com
Previous studies have shown that the high mortality caused by viruses such as severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus primarily results from …

Recent advances in passive immunotherapies for COVID-19: The Evidence-Based approaches and clinical trials

P Farhangnia, S Dehrouyeh, AR Safdarian… - International …, 2022 - Elsevier
In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged,
causing a global pandemic called COVID-19. Currently, there is no definitive treatment for …

Relevance of the Bruton tyrosine kinase as a target for COVID-19 therapy

M Rada, Z Qusairy, M Massip-Salcedo… - Molecular Cancer …, 2021 - AACR
The outbreak of the novel coronavirus disease 2019 (COVID-19) has emerged as one of the
biggest global health threats worldwide. As of October 2020, more than 44 million confirmed …

Immunologic and autoimmune-related sequelae of severe Acute Respiratory Syndrome Coronavirus 2 infection: clinical symptoms and mechanisms of Disease

A Ramasamy, C Wang, WM Brode… - Physical Medicine and …, 2023 - Elsevier
The coronavirus disease 2019 (COVID-19) pandemic has presented a serious public health
threat, resulting in more than 600 million infections worldwide and 6 million fatalities. 1 The …

Curtailing virus-induced inflammation in respiratory infections: emerging strategies for therapeutic interventions

AA Globenko, GV Kuzin, AV Rydlovskaya… - Frontiers in …, 2023 - frontiersin.org
Acute respiratory viral infections (ARVI) are the most common illnesses worldwide. In some
instances, mild cases of ARVI progress to hyperinflammatory responses, which are …

[HTML][HTML] COVID-19 infection in patients with mast cell disorders including mastocytosis does not impact mast cell activation symptoms

MP Giannetti, E Weller, I Alvarez-Twose… - The Journal of Allergy …, 2021 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus
responsible for the clinical syndrome coronavirus disease 2019 (COVID-19). This virus was …

Porcine cis-acting lnc-CAST positively regulates CXCL8 expression through histone H3K27ac

J Gao, H Yu, Y Pan, X Wang, H Zhang, Y Xu, W Ma… - Veterinary …, 2024 - Springer
The chemokine CXCL8, also known as the neutrophil chemotactic factor, plays a crucial role
in mediating inflammatory responses and managing cellular immune reactions during viral …

Mini-factor H modulates complement-dependent IL-6 and IL-10 release in an immune cell culture (PBMC) model: potential benefits against cytokine storm

GT Kozma, T Mészáros, T Bakos, M Hennies… - Frontiers in …, 2021 - frontiersin.org
Cytokine storm (CS), an excessive release of proinflammatory cytokines upon overactivation
of the innate immune system, came recently to the focus of interest because of its role in the …

Risk and course of COVID-19 in immunosuppressed patients with myasthenia gravis

F Stascheit, U Grittner, S Hoffmann, P Mergenthaler… - Journal of …, 2023 - Springer
Background Patients with myasthenia gravis (MG) are potentially prone for a severe COVID-
19 course, but there are limited real-world data available on the risk associated with COVID …

Targeting macrophage dysregulation for viral infections: Novel targets for immunomodulators

MD Reece, RR Taylor, C Song… - Frontiers in …, 2021 - frontiersin.org
A major barrier to human immunodeficiency virus (HIV-1) cure is the latent viral reservoir,
which persists despite antiretroviral therapy (ART), including across the non-dividing …