SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageing

AVW Nunn, GW Guy, W Brysch, SW Botchway… - Immunity & …, 2020 - Springer
Infection with SARs-COV-2 displays increasing fatality with age and underlying co-morbidity,
in particular, with markers of the metabolic syndrome and diabetes, which seems to be …

[HTML][HTML] The COVID-19 infection in children and its association with the immune system, prenatal stress, and neurological complications

S Khan, R Siddique, X Hao, Y Lin, Y Liu… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Abstract The Coronavirus disease 2019 (COVID-19)” caused by the “severe acute
respiratory syndrome corona virus 2 (SARS-CoV-2)” has caused huge losses to the world …

A novel definition and treatment of hyperinflammation in COVID-19 based on purinergic signalling

D Hasan, A Shono, CK van Kalken, PJ van der Spek… - Purinergic …, 2022 - Springer
Hyperinflammation plays an important role in severe and critical COVID-19. Using
inconsistent criteria, many researchers define hyperinflammation as a form of very severe …

DEspRhigh neutrophils are associated with critical illness in COVID-19

JT deKay, IF Emery, J Rud, A Eldridge, C Lord… - Scientific reports, 2021 - nature.com
SARS-CoV-2 infection results in a spectrum of outcomes from no symptoms to widely
varying degrees of illness to death. A better understanding of the immune response to SARS …

Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABAB-ergic activity and cortical plasticity in long COVID-19 syndrome

V Versace, P Ortelli, S Dezi, D Ferrazzoli… - Clinical …, 2023 - Elsevier
Objective Transcranial magnetic stimulation (TMS) studies showed that patients with
cognitive dysfunction and fatigue after COVID-19 exhibit impaired cortical GABA B-ergic …

A simple model of COVID-19 explains disease severity and the effect of treatments

S Sanche, T Cassidy, P Chu, AS Perelson… - Scientific Reports, 2022 - nature.com
Considerable effort has been made to better understand why some people suffer from
severe COVID-19 while others remain asymptomatic. This has led to important clinical …

Pathological effects of SARS-CoV-2 on hematological and immunological cells: Alterations in count, morphology, and function

E Ahmadi, Z Bagherpour, E Zarei… - Pathology-Research and …, 2022 - Elsevier
Abstract The novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the
causative agent of COVID-19 outbreak, spread rapidly and infected more than 140 million …

[PDF][PDF] Stimulus-specific responses in innate immunity: Multilayered regulatory circuits

S Luecke, KM Sheu, A Hoffmann - Immunity, 2021 - cell.com
Immune sentinel cells initiate immune responses to pathogens and tissue injury and are
capable of producing highly stimulus-specific responses. Insight into the mechanisms …

High‐resolution analysis of individual spike peptide‐specific CD4+ T‐cell responses in vaccine recipients and COVID‐19 patients

H Karsten, L Cords, T Westphal… - Clinical & …, 2022 - Wiley Online Library
Objectives Potential differences in the breadth, distribution and magnitude of CD4+ T‐cell
responses directed against the SARS‐CoV‐2 spike glycoprotein between vaccinees, COVID …

Immunogenetic association underlying severe COVID-19

K McCoy, A Peterson, Y Tian, Y Sang - Vaccines, 2020 - mdpi.com
SARS-CoV2 has caused the current pandemic of new coronavirus disease 2019 (COVID-
19) worldwide. Clinical outcomes of COVID-19 illness range broadly from asymptotic and …