Rapid recruitment of neutrophils to an inflamed site is one of the hallmarks of an effective
host defense mechanism. The main pathway through which this happens is by the innate …

New strategies to rapidly develop broad-spectrum antiviral therapies are urgently required
for emerging and re-emerging viruses. Host-targeting antivirals (HTAs) that target the …

Aiming to reduce mortality in COVID-19 with severe respiratory failure we administered a
combined rescue treatment (COMBI) on top of standard-of-care (SOC: dexamethasone …

Since its outbreak in December 2019, the coronavirus disease 2019 (COVID-19) pandemic,
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to an …

The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health crisis affecting …

The continually evolving severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic has resulted in a vast number of either acute or chronic medical impairments of a …

Background: Among the several therapeutic options assessed for the treatment of
coronavirus disease 2019 (COVID-19), tocilizumab (TCZ), an antagonist of the interleukine …

Clinical knowledge about SARS-CoV-2 infection mechanisms and COVID-19
pathophysiology have enormously increased during the pandemic. Nevertheless, because …

Objectives: The purpose of the present study was to assess and describe the severity of
symptoms reported by Covid-19 positive patients who vaped (smoked e-cigarettes) when …

The pandemic of the coronavirus disease 2019 (COVID-19) has created the largest global
health crisis in almost a century. Low frequencies of functional SARS-CoV-2-specific CD4+ …