Preoperative treatment with mFOLFIRINOX or Gemcitabine/Nab-paclitaxel+/-isotoxic high-dose stereotactic body Radiation Therapy (iHD-SBRT) for borderline …

C Bouchart, J Navez, I Borbath, K Geboes… - BMC cancer, 2023 - Springer
Background For patients with pancreatic ductal adenocarcinoma (PDAC), surgical resection
remains the only potentially curative treatment. Surgery is generally followed by …

[HTML][HTML] Nab-paclitaxel plus gemcitabine as first-line treatment for advanced pancreatic cancer: a systematic review and meta-analysis

Y Zhang, J Xu, J Hua, J Liu, C Liang, Q Meng… - Journal of …, 2019 - ncbi.nlm.nih.gov
To evaluate the effectiveness of nab-paclitaxel plus gemcitabine (NG) as a first-line
treatment for advanced pancreatic cancer. A meta-analysis was performed to assess the …

[HTML][HTML] Comparison of clinical outcomes of borderline resectable pancreatic cancer according to the neoadjuvant chemo-regimens: gemcitabine versus FOLFIRINOX

YJ Choi, Y Byun, JS Kang, HS Kim, Y Han, H Kim… - Gut and liver, 2021 - ncbi.nlm.nih.gov
Methods In this single-center retrospective study, 100 BRPC patients treated with
neoadjuvant chemotherapy and resection from 2008 to 2018 were reviewed. Clinical …

Neoadjuvant chemotherapy and radiotherapy outcomes in borderline‐resectable and locally‐advanced pancreatic cancer patients

GP Botta, TR Huynh, SR Spierling‐Bagsic… - Cancer …, 2023 - Wiley Online Library
Background There is no agreed upon standard of care for borderline‐resectable pancreatic
cancer (BRPC) or locally‐advanced pancreatic cancer (LAPC) patients regarding the benefit …

Sequestsome-1/p62-targeted small molecules for pancreatic cancer therapy

J Cuyler, P Murthy, NG Spada, TF McGuire… - Drug Discovery …, 2022 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is characterized by heightened autophagy and
systemic immune dysfunction. Modest improvements in clinical outcomes have been …

Dihydrotanshinone I inhibits pancreatic cancer progression via hedgehog/gli signal pathway

W Huang, Y Dai, L Xu, Y Mao… - Current Cancer Drug …, 2023 - ingentaconnect.com
Introduction: Pancreatic cancer is highly fatal and its incidence is rising worldwide. Its poor
prognosis is attributed to a lack of effective diagnostic and therapeutic strategies …

CT-diagnosed extra-pancreatic extension of pancreatic ductal adenocarcinoma is a more reliable prognostic factor for survival than pathology-diagnosed extension

F Toshima, D Inoue, K Yoshida, A Izumozaki… - European …, 2022 - Springer
Objectives To determine the correlation between CT-diagnosed extra-pancreatic extension
of pancreatic ductal adenocarcinoma (PDAC), pathology-diagnosed extra-pancreatic …

Prognostic impact of intraoperative peritoneal cytology after neoadjuvant therapy for potentially resectable pancreatic cancer

S Aoki, M Mizuma, H Hayashi, S Yoshimachi, T Hata… - Pancreatology, 2020 - Elsevier
Background Neoadjuvant therapy (NAT) is considered a potential approach to improve
survival for patients with pancreatic adenocarcinoma (PA). The objective of this study was to …

Pathologic tumor response to neoadjuvant therapy in resected pancreatic cancer: does it affect prognosis?

G Donisi, G Nappo, M Pacilli, GL Capretti… - Updates in Surgery, 2023 - Springer
Neoadjuvant therapy (NAT)+ surgical resection for pancreatic cancer (PC) has gained
consensus in recent years. Pathological response (PR) is generally assessed according to …

Guidelines for the diagnosis and treatment of pancreatic cancer in China (2021)

Y Yang, X Bai, D Bian, S Cai, R Chen, F Cao… - Journal of …, 2021 - mednexus.org
The incidence of pancreatic cancer has been rising worldwide, and its clinical diagnosis and
treatment remain a great challenge. To present the update and improvements in the clinical …