Locally advanced pancreatic cancer: work-up, staging, and local intervention strategies

E van Veldhuisen, C van den Oord, LJ Brada… - Cancers, 2019 - mdpi.com
Locally advanced pancreatic cancer (LAPC) has several definitions but essentially is a
nonmetastasized pancreatic cancer, in which upfront resection is considered not beneficial …

FOLFIRINOX as initial treatment for localized pancreatic adenocarcinoma: a retrospective analysis by the Trans-Atlantic Pancreatic Surgery Consortium

QP Janssen, JL Van Dam… - JNCI: Journal of the …, 2022 - academic.oup.com
Background Large pragmatic studies of patients who received 5-fluorouracil with leucovorin,
irinotecan, and oxaliplatin ([m] FOLFIRINOX) as initial treatment for localized pancreatic …

Systematic review of surgical and percutaneous irreversible electroporation in the treatment of locally advanced pancreatic cancer

D Moris, N Machairas, DI Tsilimigras… - Annals of surgical …, 2019 - Springer
Objective The aim of the present systematic review was to collect, analyze, and critically
evaluate the role of irreversible electroporation (IRE) in locally advanced pancreatic cancer …

Efficacy and safety of neoadjuvant gemcitabine plus nab-paclitaxel in borderline resectable and locally advanced pancreatic cancer—a systematic review and meta …

M Damm, L Efremov, B Birnbach, G Terrero, J Kleeff… - Cancers, 2021 - mdpi.com
Simple Summary Due to the availability of effective combination chemotherapies such as
gemcitabine/nab-paclitaxel (GNP) or FOLFIRINOX, neoadjuvant treatment of borderline …

Neoadjuvant gemcitabine and nab‐paclitaxel for borderline resectable pancreatic cancers: intention‐to‐treat analysis compared with upfront surgery

Y Inoue, A Saiura, A Oba, Y Ono, Y Mise… - Journal of Hepato …, 2021 - Wiley Online Library
Abstract Background/Purpose We evaluated efficacy of neoadjuvant therapy with
gemcitabine and nab‐paclitaxel (GNP‐NAT) in borderline resectable pancreatic cancer (BR …

Neoadjuvant therapy versus upfront surgery in resectable pancreatic cancer according to intention-to-treat and per-protocol analysis: a systematic review and meta …

YS Lee, JC Lee, SY Yang, J Kim, JH Hwang - Scientific reports, 2019 - nature.com
The effectiveness of neoadjuvant therapy (NAT) remains unclear in resectable pancreatic
cancer (PC) as compared with upfront surgery (US). The aim of this study was to investigate …

The prognostic value of CA19-9 response after neoadjuvant therapy in patients with pancreatic cancer: a systematic review and pooled analysis

C Ye, A Sadula, S Ren, X Guo, M Yuan, C Yuan… - Cancer Chemotherapy …, 2020 - Springer
Background Pancreatic cancer (PC) is a highly aggressive and refractory disease, with
disappointing 5-year survival rates. Regarding the wide application of neoadjuvant …

Immunotherapy for pancreatic ductal adenocarcinoma

E Carpenter, S Nelson, F Bednar, C Cho… - Journal of surgical …, 2021 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) remains a lethal cancer with an urgent need for
better medical therapies. Efforts have been made to investigate the efficacy of …

S3-Leitlinie zum exokrinen pankreaskarzinom–langversion 2.0–dezember 2021–AWMF-registernummer: 032/010ol

T Seufferlein, J Mayerle, S Böck… - Zeitschrift für …, 2022 - thieme-connect.com
Familiäres Pankreaskarzinom (S. e836): Hier wird erstmals definiert, welchen Angehörigen
von Patienten mit familiärem Pankreaskarzinom welche genetischen Untersuchungen zur …

[HTML][HTML] Implications of the microbiome in the development and treatment of pancreatic cancer: Thinking outside of the box by looking inside the gut

Q Yu, C Jobin, RM Thomas - Neoplasia, 2021 - Elsevier
Pancreatic ductal adenocarcinoma is the third leading cause of cancer-related death in the
United States. As one of the most lethal cancer types, the prognosis for patients diagnosed …