Diabetes, metformin and the clinical course of Covid-19: outcomes, mechanisms and suggestions on the therapeutic use of metformin

CJ Bailey, M Gwilt - Frontiers in pharmacology, 2022 - frontiersin.org
Objectives: Pre-existing or new diabetes confers an adverse prognosis in people with Covid-
19. We reviewed the clinical literature on clinical outcomes in metformin-treated subjects …

Mitochondrial oxidative stress, mitochondrial ROS storms in long COVID pathogenesis

K Noonong, M Chatatikun, S Surinkaew… - Frontiers in …, 2023 - frontiersin.org
Significance This review discusses the coronavirus disease 2019 (COVID-19)
pathophysiology in the context of diabetes and intracellular reactions by COVID-19 …

[HTML][HTML] Improved LSTM-based deep learning model for COVID-19 prediction using optimized approach

L Zhou, C Zhao, N Liu, X Yao, Z Cheng - Engineering applications of …, 2023 - Elsevier
Individuals in any country are badly impacted both economically and physically whenever
an epidemic of infectious illnesses breaks out. A novel coronavirus strain was responsible …

Rate and predictors of hesitancy toward SARS-CoV-2 vaccine among type 2 diabetic patients: results from an Italian survey

F Guaraldi, M Montalti, Z Di Valerio, E Mannucci… - Vaccines, 2021 - mdpi.com
Vaccine hesitancy (VH) has been identified as one of the major health concerns of our time
by the World Health Organization. It may prove especially detrimental in the light of the …

Association of serum C-reactive protein (CRP) and D-dimer concentration on the severity of COVID-19 cases with or without diabetes: a systematic review and meta …

H Debi, ZT Itu, MT Amin, F Hussain… - Expert Review of …, 2022 - Taylor & Francis
ABSTRACT Introduction Coronavirus disease (COVID-19) is a highly contagious disease
that poses major public health risks. Fewer studies link high CRP and D-dimer levels to …

Mental health burden of patients with diabetes before and after the initial outbreak of COVID-19: predictors of mental health impairment

S Moradian, M Teufel, L Jahre, V Musche, M Fink… - BMC Public Health, 2021 - Springer
Background The COVID-19 pandemic is affecting people's mental health worldwide.
Patients with diabetes are at risk for a severe course of illness when infected with SARS …

Diabetes, COVID‐19, and questions unsolved

F D'Souza, R Buzzetti, P Pozzilli - … /Metabolism Research and …, 2023 - Wiley Online Library
Recent evidence suggests a role for Diabetes Mellitus in adverse outcomes from COVID‐19
infection; yet the underlying mechanisms are not clear. Moreover, attention has turned to …

Diabetic ketoacidosis in patients with SARS-CoV-2: a systematic review and meta-analysis

S Alhumaid, A Al Mutair, Z Al Alawi, AA Rabaan… - Diabetology & metabolic …, 2021 - Springer
Background One possible reason for increased mortality due to SARS-CoV-2 in patients
with diabetes is from the complication of diabetic ketoacidosis (DKA). Objectives To re …

Metformin use in patients hospitalized with COVID-19: Lower inflammation, oxidative stress, and thrombotic risk markers and better clinical outcomes

A Usman, KP Bliden, A Cho, N Walia, C Jerjian… - Journal of Thrombosis …, 2022 - Springer
Diabetes mellitus (DM) is associated with a greater risk of COVID-19 and an increased
mortality when the disease is contracted. Metformin use in patients with DM is associated …

Impact of diabetes on COVID-19 patient health outcomes in a vulnerable racial minority community

S Hamaway, U Nwokoma, M Goldberg, MO Salifu… - PLoS …, 2023 - journals.plos.org
Background Diabetes is a growing health concern in the United States and especially New
York City. New York City subsequently became an epicenter for the coronavirus pandemic in …