Transmembrane proteins (TMPs) play important roles in cells, ranging from transport
processes and cell adhesion to communication. Many of these functions are mediated by …

Accurate protein structure prediction using computational methods remains a challenge in
molecular biology. Recent advances in AI-powered algorithms provide a transformative …

Intrinsically disordered proteins (IDPs) are important for a broad range of biological functions
and are involved in many diseases. An understanding of intrinsic disorder is key to develop …

Intrinsically disordered proteins and protein regions make up 20-40% of most eukaryotic
proteomes where they play essential roles in a wide gamut of cellular processes, from …

The β-sheet–rich amyloid core is the defining feature of protein aggregates associated with
neurodegenerative disorders. Recent investigations have revealed that there exist multiple …

The deposition of amyloid-β peptide (Aβ) in the brain is a critical event in the progression of
Alzheimer's disease (AD). This Aβ deposition could be prevented by directed enhancement …

The viability of viral-derived nanoparticles (virions and VLPs) aimed to nanobiotechnological
functionalizations of the coat protein (CP) of turnip mosaic virus has been studied by means …

We expand studies of AlphaFold2 (AF2) in the context of intrinsic disorder prediction by
comparing it against a broad selection of 20 accurate, popular and recently released …

The sequence-based predictors of RNA-binding residues (RBRs) are trained on either
structure-annotated or disorder-annotated binding regions. A recent study of predictors of …

Intrinsically disordered proteins (IDPs) play a vital role in various biological processes and
have attracted increasing attention in the past few decades. Predicting IDPs from the primary …