Significance: Selenoproteins incorporate the essential nutrient selenium into their
polypeptide chain. Seven members of this family reside in the endoplasmic reticulum (ER) …

Exposure to ionizing radiation (IR) is a common occurrence in clinical practice and incidents
involving nuclear detonation or nuclear reactor accidents. IR triggers cellular events that …

Background The skeletal muscle of pigs is vulnerable to oxidative damage, resulting in
growth retardation. Selenoproteins are important components of antioxidant systems for …

Selenium (Se), apart from iodine, iron, and calcium, is one of the nutrient-derived key
elements strongly affecting the endocrine system. However, no specific hormonal “feedback” …

Eighteen years ago, unexpected epileptic seizures in Selenop-knockout mice pointed to a
potentially novel, possibly underestimated, and previously difficult to study role of selenium …

Selenoprotein N (SEPN1) is critical to the normal muscular physiology. Mutation of SEPN1
can raise congenital muscular disorder in human. It is also central to maturation and …

Selenophosphate synthetases use selenium and ATP to synthesize selenophosphate. This
is required for biological utilization of selenium, most notably for the synthesis of the non …

Significance: Bioinformatics has brought important insights into the field of selenium
research. The progress made in the development of computational tools in the last two …

Selenoprotein S (selenos) is a small, intrinsically disordered membrane protein that is
associated with various cellular functions, such as inflammatory processes, cellular stress …

Selenium (Se) is an essential micronutrient that plays a key role in regulating the immune
system. T cells are of particular interest due to their important role in promoting adaptive …