What does the taste system tell us about the nutritional composition and toxicity of foods?

JI Glendinning - The Pharmacology of Taste, 2021 - Springer
One of the distinctive features of the human taste system is that it categorizes food into a few
taste qualities–eg, sweet, salty, sour, bitter, and umami. Here, I examined the functional …

Inferences of African evolutionary history from genomic data

MH Beltrame, MA Rubel, SA Tishkoff - Current Opinion in Genetics & …, 2016 - Elsevier
Africa is the origin of anatomically modern humans and a continent of linguistic, cultural,
environmental, phenotypic, and genetic diversity. However, African populations remain …

Population structure and infectious disease risk in southern Africa

C Uren, M Möller, PD van Helden, BM Henn… - Molecular genetics and …, 2017 - Springer
The KhoeSan populations are the earliest known indigenous inhabitants of southern Africa.
The relatively recent expansion of Bantu-speaking agropastoralists, as well as European …

Natural selection of immune and metabolic genes associated with health in two lowland Bolivian populations

AJ Lea, A Garcia, J Arevalo… - Proceedings of the …, 2023 - National Acad Sciences
A growing body of work has addressed human adaptations to diverse environments using
genomic data, but few studies have connected putatively selected alleles to phenotypes …

Signatures of convergent evolution and natural selection at the alcohol dehydrogenase gene region are correlated with agriculture in ethnically diverse Africans

MA McQuillan, A Ranciaro, MEB Hansen… - Molecular Biology …, 2022 - academic.oup.com
The alcohol dehydrogenase (ADH) family of genes encodes enzymes that catalyze the
metabolism of ethanol into acetaldehyde. Nucleotide variation in ADH genes can affect the …

The genomic echoes of the last Green Sahara on the Fulani and Sahelian people

E D'Atanasio, F Risi, F Ravasini, F Montinaro… - Current Biology, 2023 - cell.com
The population history of the Sahara/Sahelian belt is understudied, despite previous work
highlighting complex dynamics. 1, 2, 3, 4, 5, 6, 7 The Sahelian Fulani, ie, the largest …

The introduction of pastoralism to southernmost Africa: Thoughts on new contributions to an ongoing debate

J Orton - Azania: Archaeological Research in Africa, 2015 - Taylor & Francis
One of the longest-standing debates in African archaeology concerns the introduction of
herding to southern Africa and the resulting associated cultural changes. Two short books …

Reconciling Differences in Pool-GWAS Between Populations: A Case Study of Female Abdominal Pigmentation in Drosophila melanogaster

L Endler, AJ Betancourt, V Nolte, C Schlötterer - Genetics, 2016 - academic.oup.com
The degree of concordance between populations in the genetic architecture of a given trait
is an important issue in medical and evolutionary genetics. Here, we address this problem …

The evolution of lactase persistence: milk consumption, insulin-like growth factor I, and human life-history parameters

AS Wiley - The Quarterly Review of Biology, 2018 - journals.uchicago.edu
For most mammals and humans, production of the intestinal enzyme lactase is a life-history
trait that corresponds roughly to the duration of nursing. However, some human populations …

Equating language, genes and subsistence? The appearance of herding in southern Africa

I Guillemard - Azania: Archaeological Research in Africa, 2020 - Taylor & Francis
The combined use of linguistic, genetic and archaeological studies for establishing
migration models is common in southern African research on pastoralism. According to …