With the growing prevalence of cardiovascular disease (CVD), there is an urgent need to
explore non-conventional therapeutic measures to alleviate the burden of CVD on global …

Melatonin is a fascinating molecule that has captured the imagination of many scientists
since its discovery in 1958. In recent times, the focus has changed from investigating its …

The endoplasmic reticulum (ER) governs the proper folding of polypeptides and proteins
through various chaperones and enzymes residing within the ER organelle. Perturbation in …

Cardiovascular disease (CVD) is a group of systemic disorders threatening human health
with complex pathogenesis, among which mitochondrial energy metabolism reprogramming …

Mitophagy is a type of autophagy that can selectively eliminate damaged and depolarized
mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways …

Melatonin is a neurohormone that is mainly secreted by the pineal gland. It coordinates the
work of the superior biological clock and consequently affects many processes in the human …

Abstract Background The Chinese herbal compound Xinmaikang (XMK) is effective in
treating atherosclerosis (AS), although the associated mechanisms of action remain unclear …

Alcohol‐related liver disease (ARLD) refers to a spectrum of hepatic damage triggered by
excessive alcohol intake, resulting in inflamed and swollen livers, ultimately, liver cirrhosis …

Mitochondria, the intracellular organelles for cellular aerobic respiration and energy
production, play an important role in the regulation of cell metabolism and cell fate …

Aging triggers a wide range of cellular and molecular aberrations in the body, giving rise to
inflammation and associated diseases. In particular, aging is associated with persistent low …