A novel redox-sensitive polycationic amphiphile (2S3) with disulphide linkers for nucleic
acid delivery was developed. Cationic liposomes formed by 2S3 and the helper lipid DOPE …

Over the past decade, mRNA-based therapy has displayed significant promise in a wide
range of clinical applications. The most striking example of the leap in the development of …

The performance of cationic liposomes for delivery of therapeutic nucleic acids in vivo can
be improved and specifically tailored to certain types of cargo and target cells by …

Limitations regarding the targeted delivery of therapeutic nucleic acids into cancer cells can
be overcome by developing a non-viral delivery system equipped with folate-containing …

ABSTRACT Purpose Successful genetically engineered Dendritic Cell (DC) can enhance
DC's antigen presentation and lymph node migration. The present study aims to genetically …

A dendritic cell (DC) networking system has become an attractive approach in cancer
immunotherapy. Successful DC gene engineering depends on the development of …

Three novel polycationic gemini amphiphiles with different spacers were developed and
evaluated in terms of their physiochemical properties and transfection efficiencies. Cationic …

树突状细胞(dendritic cells, DCs) 是一类多功能抗原提呈细胞, 在固有免疫和适应性免疫应答的
启动及调控中发挥着重要作用. 目前, 大量研究表明机体可通过多种方式调动和调节DC 的功能 …

Dendritic cells (DCs) are essential to many aspects of immune defense development and
regulation. They provide important targets for prophylactic and therapeutic delivery. While …

Purpose: Spinal cord injury (SCI) has a damaging impact on patients, amid being a
worldwide problem with no effective treatment. Herein, we reported a method for functional …