Gene therapy is a promising method for the treatment of various diseases by introducing
therapeutic nucleic acids, for the delivery of which cationic liposomes are widely used. This …

The absence of highly effective delivery systems is a major challenge for gene therapy. Our
work was aimed at the development of novel cationic liposomes possessing high …

The oncogenic bcr/abl1 fusion gene is a chronic myelogenous leukemia (CML)-specific
antigen which is absent in normal tissues. This makes bcr/abl1 a perfect target for …

The field of medicine and pharmaceuticals has experienced revolutionary changes due to
the development of nanotechnology. Materials or their constructions with size less than 100 …

Background: Cationic liposomes (CLs) based messenger RNA (mRNA) vaccine has been a
promising approach for cancer treatment. However, rapid lung accumulation after intraveous …

Gene delivery relies upon the encapsulation of a gene of interest, which is then ideally
delivered to target cells. For gene therapy applications, viral vectors are the most efficient …

Возможность адресной доставки препаратов к определенным органам-мишеням,
тканям и клеткам открыла невероятные перспективы для разработки новых способов …

Aim: We aimed to test the hypothesis that loading of dendritic cells (DCs) with both viral and
tumor-specific antigens would enhance the efficacy antitumor DC-based therapy applied …

Non-viral gene delivery strategies have attracted significant interest in the development of
novel therapeutic approaches as well as for basic and applied research in vitro. Compared …